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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 1, Iss. 1 — Aug. 2, 2010
  • pp: 41–46

Pseudo-random single photon counting: a high-speed implementation

Qiang Zhang, Ling Chen, and Nanguang Chen  »View Author Affiliations


Biomedical Optics Express, Vol. 1, Issue 1, pp. 41-46 (2010)
http://dx.doi.org/10.1364/BOE.1.000041


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Abstract

Pseudo-random single photon counting (PRSPC) is a new time-resolved optical measurement method which combines the spread spectrum time-resolved method with single photon counting. A pseudo-random bit sequence is used to modulate a continuous wave laser diode, while single photon counting is used to build up the optical signal in response to the modulated excitation. Periodic cross-correlation is performed to obtain the temporal profile of the subject of interest. Compared with conventional time-correlated single photon counting (TCSPC), PRSPC enjoys many advantages such as low cost and high count rate without compromising the sensitivity and time-resolution. In this paper, we report a PRSPC system that can be used for high-speed acquisition of the temporal point spread function of diffuse photons. It can reach a photon count rate as high as 3 Mcps (counts per second). Phantom experiments have been conducted to demonstrate the system performance.

© 2010 OSA

OCIS Codes
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(300.6500) Spectroscopy : Spectroscopy, time-resolved

ToC Category:
Spectroscopic Diagnostics

History
Original Manuscript: June 1, 2010
Revised Manuscript: June 22, 2010
Manuscript Accepted: July 6, 2010
Published: July 13, 2010

Citation
Qiang Zhang, Ling Chen, and Nanguang Chen, "Pseudo-random single photon counting: a high-speed implementation," Biomed. Opt. Express 1, 41-46 (2010)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-1-1-41


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