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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 1, Iss. 2 — Sep. 1, 2010
  • pp: 537–552

Doppler imaging with dual-detection full-range frequency domain optical coherence tomography

Panomsak Meemon, Kye-Sung Lee, and Jannick P. Rolland  »View Author Affiliations


Biomedical Optics Express, Vol. 1, Issue 2, pp. 537-552 (2010)
http://dx.doi.org/10.1364/BOE.1.000537


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Abstract

Most of full-range techniques for Frequency Domain Optical Coherence Tomography (FD-OCT) reported to date utilize the phase relation between consecutive axial lines to reconstruct a complex interference signal and hence may exhibit degradation in either mirror image suppression performance or detectable velocity dynamic range or both when monitoring a moving sample such as flow activity. We have previously reported a technique of mirror image removal by simultaneous detection of the quadrature components of a complex spectral interference called a Dual-Detection Frequency Domain OCT (DD-FD-OCT) [Opt. Lett. 35, 1058-1060 (2010)]. The technique enables full range imaging without any loss of acquisition speed and is intrinsically less sensitive to phase errors generated by involuntary movements of the subject. In this paper, we demonstrate the application of the DD-FD-OCT to a phase-resolved Doppler imaging without degradation in either mirror image suppression performance or detectable velocity dynamic range that were observed in other full-range Doppler methods. In order to accommodate for Doppler imaging, we have developed a fiber-based DD-FD-OCT that more efficiently utilizes the source power compared with the previous free-space DD-FD-OCT. In addition, the velocity sensitivity of the phase-resolved DD-FD-OCT was investigated, and the relation between the measured Doppler phase shift and set flow velocity of a flow phantom was verified. Finally, we demonstrate the Doppler imaging using the DD-FD-OCT in a biological sample.

© 2010 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(280.2490) Remote sensing and sensors : Flow diagnostics
(110.4153) Imaging systems : Motion estimation and optical flow

ToC Category:
Optical Coherence Tomography

History
Original Manuscript: May 18, 2010
Revised Manuscript: July 9, 2010
Manuscript Accepted: August 8, 2010
Published: August 10, 2010

Citation
Panomsak Meemon, Kye-Sung Lee, and Jannick P. Rolland, "Doppler imaging with dual-detection full-range frequency domain optical coherence tomography," Biomed. Opt. Express 1, 537-552 (2010)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-1-2-537


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