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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 1, Iss. 3 — Oct. 1, 2010
  • pp: 780–790

Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications

Sean A. Burgess, Désirée Ratner, Brenda R. Chen, and Elizabeth M. C. Hillman  »View Author Affiliations


Biomedical Optics Express, Vol. 1, Issue 3, pp. 780-790 (2010)
http://dx.doi.org/10.1364/BOE.1.000780


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Abstract

Laminar optical tomography (LOT) is a recently developed technique for depth-resolved in vivo imaging of absorption and fluorescence contrast. Until now, LOT has been implemented in a benchtop configuration, limiting accessibility to tissues and restricting imaging applications. Here we report on LOT implemented through an articulating arm and a fiber optic image bundle allowing flexible imaging for a range of clinical applications. We quantify the performance of these two implementations by imaging a tissue mimicking phantom.

© 2010 OSA

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation

ToC Category:
Clinical Instrumentation

History
Original Manuscript: June 4, 2010
Revised Manuscript: August 28, 2010
Manuscript Accepted: August 31, 2010
Published: September 2, 2010

Virtual Issues
Bio-Optics in Clinical Application, Nanotechnology, and Drug Discovery (2010) Biomedical Optics Express

Citation
Sean A. Burgess, Désirée Ratner, Brenda R. Chen, and Elizabeth M. C. Hillman, "Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications," Biomed. Opt. Express 1, 780-790 (2010)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-1-3-780


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