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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 1, Iss. 3 — Oct. 1, 2010
  • pp: 848–860

Formation and characterization of an ideal excitation beam geometry in an optofluidic device

Benjamin R. Watts, Thomas Kowpak, Zhiyi Zhang, Chang-Qing Xu, and Shiping Zhu  »View Author Affiliations


Biomedical Optics Express, Vol. 1, Issue 3, pp. 848-860 (2010)
http://dx.doi.org/10.1364/BOE.1.000848


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Abstract

An optimal excitation beam shape is necessary to perform reliable flow cytometric analysis but has so far not been implemented in a photonic-microfluidic integrated (i.e. optofluidic) device. We have achieved this feature by integrating a 1D lens system with planar waveguides and microfluidic channel on a substrate using one patterning material via a one-shot process. In this paper, we report the method of design and the performance of specifically formed excitation regions shaped to be ideal for reducing double detections, improving SNR, and for reliable detection in a flow cytometry application. Demonstration of different sizes via changes to lens design shows the ability to control the width of the shaped beam according to a targeted detection.

© 2010 OSA

OCIS Codes
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.2945) Medical optics and biotechnology : Illumination design
(130.3990) Integrated optics : Micro-optical devices

ToC Category:
Microfluidics

History
Original Manuscript: June 17, 2010
Revised Manuscript: August 9, 2010
Manuscript Accepted: August 16, 2010
Published: September 14, 2010

Citation
Benjamin R. Watts, Thomas Kowpak, Zhiyi Zhang, Chang-Qing Xu, and Shiping Zhu, "Formation and characterization of an ideal excitation beam geometry in an optofluidic device," Biomed. Opt. Express 1, 848-860 (2010)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-1-3-848


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