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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 1, Iss. 3 — Oct. 1, 2010
  • pp: 998–1013

Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme

Vadim Y. Soloviev, Cosimo D'Andrea, P. Surya Mohan, Gianluca Valentini, Rinaldo Cubeddu, and Simon R. Arridge  »View Author Affiliations

Biomedical Optics Express, Vol. 1, Issue 3, pp. 998-1013 (2010)

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We develop discontinuous Galerkin framework for solving direct and inverse problems in fluorescence diffusion optical tomography in turbid media. We show the advantages and the disadvantages of this method by comparing it with previously developed framework based on the finite volume discretization. The reconstruction algorithm was used with time-gated experimental dataset acquired by imaging a highly scattering cylindrical phantom concealing small fluorescent tubes. Optical parameters, quantum yield and lifetime were simultaneously reconstructed. Reconstruction results are presented and discussed.

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OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(290.0290) Scattering : Scattering
(290.7050) Scattering : Turbid media

ToC Category:
Image Reconstruction and Inverse Problems

Original Manuscript: August 19, 2010
Revised Manuscript: September 7, 2010
Manuscript Accepted: September 12, 2010
Published: September 20, 2010

Vadim Y. Soloviev, Cosimo D'Andrea, P. Surya Mohan, Gianluca Valentini, Rinaldo Cubeddu, and Simon R. Arridge, "Fluorescence lifetime optical tomography with discontinuous Galerkin discretisation scheme," Biomed. Opt. Express 1, 998-1013 (2010)

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