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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 1, Iss. 4 — Nov. 1, 2010
  • pp: 1060–1074

Characterizing the localized surface plasmon resonance behaviors of Au nanorings and tracking their diffusion in bio-tissue with optical coherence tomography

Cheng-Kuang Lee, Hung-Yu Tseng, Chia-Yun Lee, Shou-Yen Wu, Ting-Ta Chi, Kai-Min Yang, Han-Yi Elizabeth Chou, Meng-Tsan Tsai, Jyh-Yang Wang, Yean-Woei Kiang, Chun-Pin Chiang, and C. C. Yang  »View Author Affiliations

Biomedical Optics Express, Vol. 1, Issue 4, pp. 1060-1074 (2010)

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The characterization results of the localized surface plasmon resonance (LSPR) of Au nanorings (NRs) with optical coherence tomography (OCT) are first demonstrated. Then, the diffusion behaviors of Au NRs in mouse liver samples tracked with OCT are shown. For such research, aqueous solutions of Au NRs with two different localized surface plasmon resonance (LSPR) wavelengths are prepared and characterized. Their LSPR-induced extinction cross sections at 1310 nm are estimated with OCT scanning of solution droplets on coverslip to show reasonably consistent results with the data at individual LSPR wavelengths and at 1310 nm obtained from transmission measurements of Au NR solutions and numerical simulations. The resonant and non-resonant Au NRs are delivered into mouse liver samples for tracking Au NR diffusion in the samples through continuous OCT scanning for one hour. With resonant Au NRs, the average A-mode scan profiles of OCT scanning at different delay times clearly demonstrate the extension of strong backscattering depth with time. The calculation of speckle variance among successive OCT scanning images, which is related to the local transport speed of Au NRs, leads to the illustrations of downward propagation and spreading of major Au NR motion spot with time.

© 2010 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(240.6680) Optics at surfaces : Surface plasmons

ToC Category:
Nanotechnology and Plasmonics

Original Manuscript: September 9, 2010
Revised Manuscript: September 28, 2010
Manuscript Accepted: September 29, 2010
Published: October 1, 2010

Virtual Issues
October 18, 2010 Spotlight on Optics

Cheng-Kuang Lee, Hung-Yu Tseng, Chia-Yun Lee, Shou-Yen Wu, Ting-Ta Chi, Kai-Min Yang, Han-Yi Elizabeth Chou, Meng-Tsan Tsai, Jyh-Yang Wang, Yean-Woei Kiang, Chun-Pin Chiang, and C. C. Yang, "Characterizing the localized surface plasmon resonance behaviors of Au nanorings and tracking their diffusion in bio-tissue with optical coherence tomography," Biomed. Opt. Express 1, 1060-1074 (2010)

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