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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 1, Iss. 4 — Nov. 1, 2010
  • pp: 1117–1126

Photoacoustic tomography: a potential new tool for prostate cancer

Xueding Wang, William W. Roberts, Paul L. Carson, David P. Wood, and J. Brian Fowlkes  »View Author Affiliations


Biomedical Optics Express, Vol. 1, Issue 4, pp. 1117-1126 (2010)
http://dx.doi.org/10.1364/BOE.1.001117


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Abstract

The feasibility of photoacoustic tomography (PAT) for noninvasive imaging of prostate cancer was explored through the study on a canine model in vivo. Imaging of blood-rich lesions mimicking prostate tumors was achieved using a commercial medical ultrasound (US) system without affecting its original imaging functions. Based on the optical contrast between hemoglobin and other tissues, PAT has demonstrated good sensitivity and high contrast-to-noise ratio in visualizing deep lesions; while US has presented the morphological features including the boundary and the urethral of the prostate. PAT of prostate cancer may facilitate improved tumor localization, staging of disease, and detection of recurrences.

© 2010 OSA

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Photoacoustic Imaging and Spectroscopy

History
Original Manuscript: September 15, 2010
Revised Manuscript: October 1, 2010
Manuscript Accepted: October 5, 2010
Published: October 7, 2010

Citation
Xueding Wang, William W. Roberts, Paul L. Carson, David P. Wood, and J. Brian Fowlkes, "Photoacoustic tomography: a potential new tool for prostate cancer," Biomed. Opt. Express 1, 1117-1126 (2010)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-1-4-1117


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