Optics InfoBase > Biomedical Optics Express > Volume 1 > Issue 4 > Page 1173
|
Hemodynamic and metabolic diffuse optical monitoring in a mouse model of hindlimb ischemiaRickson C. Mesquita, Nicolas Skuli, Meeri N. Kim, Jiaming Liang, Steve Schenkel, Amar J. Majmundar, M. Celeste Simon, and Arjun G. Yodh »View Author Affiliations
Rickson C. Mesquita,1,*
Nicolas Skuli,2,3
Meeri N. Kim,1
Jiaming Liang,1,4
Steve Schenkel,1
Amar J. Majmundar,2,5
M. Celeste Simon,2,3,6
and Arjun G. Yodh1
1Department of Physics & Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA 2Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA 3Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia, PA 19104, USA 4School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, China 5School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA 6Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA *Corresponding author: rickson@nmr.mgh.harvard.edu |
Biomedical Optics Express, Vol. 1, Issue 4, pp. 1173-1187 (2010)
http://dx.doi.org/10.1364/BOE.1.001173
View Full Text Article
Enhanced HTML 
Acrobat PDF (1423 KB)
Abstract
Murine hindlimb ischemia is a useful model for investigation of the mechanisms of peripheral arterial disease and for understanding the role of endothelial cells and generic factors affecting vascular regeneration or angiogenesis. To date, important research with these models has explored tissue reperfusion following ischemia with Laser Doppler methods, methods which provide information about superficial (~mm) vascular regeneration. In this work, we employ diffuse correlation spectroscopy (DCS) and diffuse optical spectroscopy (DOS) in mice after hindlimb ischemia. We hypothesize that vascular re-growth is not uniform in tissue, and therefore, since diffuse optical methods are capable of probing deep tissues, that the diffuse optics approach will provide a more complete picture of the angiogenesis process throughout the whole depth profile of the limb. Besides increased depth penetration, the combined measurements of DCS and DOS enable all-optical, noninvasive, longitudinal monitoring of tissue perfusion and oxygenation that reveals the interplay between these hemodynamic parameters during angiogenesis. Control mice were found to reestablish 90% of perfusion and oxygen consumption during this period, but oxygen saturation in the limb only partially recovered to about 30% of its initial value. The vascular recovery of mice with endothelial cell-specific deletion of HIF-2α was found to be significantly impaired relative to control mice, indicating that HIF-2α is important for endothelial cell functions in angiogenesis. Comparison of DOS/DCS measurements to parallel measurements in the murine models using Laser Doppler Flowmetry reveal differences in the reperfusion achieved by superficial versus deep tissue during neoangiogenesis; findings from histological analysis of blood vessel development were further correlated with these differences. In general, the combination of DCS and DOS enables experimenters to obtain useful information about oxygenation, metabolism, and perfusion throughout the limb. The results establish diffuse optics as a practical noninvasive method to evaluate the role of transcription factors, such as the endothelial cell-specific HIF-2α, in genetic ally modified mice.
© 2010 OSA
OCIS Codes
(170.1420) Medical optics and biotechnology : Biology
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5380) Medical optics and biotechnology : Physiology
ToC Category:
Cardiovascular Applications
History
Original Manuscript: August 12, 2010
Revised Manuscript: September 29, 2010
Manuscript Accepted: October 12, 2010
Published: October 15, 2010
Citation
Rickson C. Mesquita, Nicolas Skuli, Meeri N. Kim, Jiaming Liang, Steve Schenkel, Amar J. Majmundar, M. Celeste Simon, and Arjun G. Yodh, "Hemodynamic and metabolic diffuse optical monitoring in a mouse model of hindlimb ischemia," Biomed. Opt. Express 1, 1173-1187 (2010)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-1-4-1173
Sort: Author | Year | Journal | Reset
References
- P. Carmeliet, “Angiogenesis in life, disease and medicine,” Nature 438(7070), 932–936 (2005). [CrossRef] [PubMed]
- M. M. Hickey and M. C. Simon, “Regulation of angiogenesis by hypoxia and hypoxia-inducible factors,” Curr. Top. Dev. Biol. 76, 217–257 (2006). [CrossRef] [PubMed]
- K. L. Covello and M. C. Simon, “HIFs, hypoxia, and vascular development,” Curr. Top. Dev. Biol. 62, 37–54 (2004). [CrossRef] [PubMed]
- B. Zhou, M. C. Poon, W. T. Pu, and Z. C. Han, “Therapeutic neovascularization for peripheral arterial diseases: advances and perspectives,” Histol. Histopathol. 22(6), 677–686 (2007). [PubMed]
- J. A. Bertout, S. A. Patel, and M. C. Simon, “The impact of O2 availability on human cancer,” Nat. Rev. Cancer 8(12), 967–975 (2008). [CrossRef] [PubMed]
- M. Heil, I. Eitenmüller, T. Schmitz-Rixen, and W. Schaper, “Arteriogenesis versus angiogenesis: similarities and differences,” J. Cell. Mol. Med. 10(1), 45–55 (2006). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- G. L. Wang and G. L. Semenza, “Purification and characterization of hypoxia-inducible factor 1,” J. Biol. Chem. 270(3), 1230–1237 (1995). [CrossRef] [PubMed]
- H. Tian, S. L. McKnight, and D. W. Russell, “Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells,” Genes Dev. 11(1), 72–82 (1997). [CrossRef] [PubMed]
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovasc. Res. 49(3), 609–617 (2001). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- K. R. Forrester, C. Stewart, J. Tulip, C. Leonard, and R. C. Bray, “Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue,” Med. Biol. Eng. Comput. 40(6), 687–697 (2002). [CrossRef] [PubMed]
- T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010). [CrossRef]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995). [CrossRef] [PubMed]
- D. A. Boas and A. G. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997). [CrossRef]
- G. Q. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI,” Opt. Express 15(3), 1064–1075 (2007). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- V. E. Papaioannou and J. G. Fox, “Efficacy of tribromoethanol anesthesia in mice,” Lab. Anim. Sci. 43(2), 189–192 (1993). [PubMed]
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
- S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992). [CrossRef] [PubMed]
- S. Prahl, Optical properties spectra, http://omlc.ogi.edu/spectra/index.html
- S. Takatani and M. D. Graham, “Theoretical analysis of diffuse reflectance from a two-layer tissue model,” IEEE Trans. Biomed. Eng. 26(12), 656–664 (1979). [CrossRef] [PubMed]
- J. A. Nelder and R. Mead, “A simplex method for function minimization,” Comput. J. 7, 308–313 (1965).
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- D. A. Boas, J. P. Culver, J. J. Stott, and A. K. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head,” Opt. Express 10(3), 159–170 (2002). [PubMed]
- L. Gagnon, M. Desjardins, J. Jehanne-Lacasse, L. Bherer, and F. Lesage, “Investigation of diffuse correlation spectroscopy in multi-layered media including the human head,” Opt. Express 16(20), 15514–15530 (2008). [CrossRef] [PubMed]
- P. Carmeliet, “Mechanisms of angiogenesis and arteriogenesis,” Nat. Med. 6(4), 389–395 (2000). [CrossRef] [PubMed]
- W. Schaper, “Collateral circulation: past and present,” Basic Res. Cardiol. 104(1), 5–21 (2009). [CrossRef] [PubMed]
- L. H. Gray and J. M. Steadman, “Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood,” J. Physiol. 175, 161–171 (1964). [PubMed]
- K. Schmidt-Neilsen and J. L. Larimer, “Oxygen dissociation curves of mammalian blood in relation to body size,” Am. J. Physiol. 195(2), 424–428 (1958). [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
Acevedo, V. D.
Arridge, S. R.
Baker, W. B.
Bertout, J. A.
Berwick, J.
Bherer, L.
Boas, D. A.
Boengler, K.
Bosch-Marce, M.
Brandt, U.
Bray, R. C.
Buckley, E. M.
Busch, T. M.
Busch*, T. M.
Buschmann, I.
Buschmann, I. R.
Campbell, L. E.
Carmeliet, P.
Cheung, C.
Cheung, R.
Choe, R.
Cope, M.
Couffinhal, T.
Covello, K. L.
Culver, J. P.
Deindl, E.
Delpy, D. T.
Desjardins, M.
Detre, J. A.
Drexler, H.
Drinane, M.
Dunn, A. K.
Durduran, T.
Durning, S. M.
Edlow, B. L.
Eitenmüller, I.
Emanuele, M. J.
Eucker, S. A.
Evans, S. M.
Fernandez, B.
Finlay, J. C.
Floyd, T. F.
Forrester, K. R.
Fox, J. G.
Frangos, S.
Freeman, K. W.
Friedrich, C.
Friess, S. H.
Furuya, D.
Gagnon, L.
Gangula, R. D.
Gaynor, J. W.
Glatstein, E.
Grady, M. S.
Graham, M. D.
Gray, L. H.
Greenberg, J. H.
Greenberg, N. M.
Griffin, G. M.
Hahn, S. M.
Han, Z. C.
Heil, M.
Helisch, A.
Hickey, M. M.
Hoefer, I. E.
Hoge, R. D.
Ichord, R. N.
Iruela-Arispe, L.
Isner, J. M.
Jasdzewski, G.
Jehanne-Lacasse, J.
Johnston, D.
Jones, M.
Kachur, A.
Kearney, M.
Keith, B.
Kerbel, R.
Khan, N.
Kim, M. N.
Kimura, H.
Koch, C. J.
Kofke, W. A.
Korff, T.
Koscielniak, J. W.
Krishna, M. C.
Kuppusamy, P.
Larimer, J. L.
Lavallee, T.
Lee, K.
Leonard, C.
Lesage, F.
Levine, J. M.
Licht, D. J.
Limbourg, A.
Limbourg, F. P.
Liu, L.
Liu, Y. V.
Maloney-Wilensky, E.
Mandeville, J. B.
Margulies, S. S.
Martindale, J.
Mason, S. E.
Matsumoto, A.
Matsumoto, K. I.
Matsumoto, S.
Mayhew, J.
McDonald, K. R.
McKnight, S. L.
Mead, R.
Mitchell, J. B.
Montenegro, L. M.
Moss, H. E.
Na, Y.
Napp, L. C.
Nelder, J. A.
Nicolson, S. C.
Okuyama, H.
Papaioannou, V. E.
Patel, S.
Patel, S. A.
Pearlman, J. D.
Piek, J. J.
Podzuweit, T.
Poldrack, R. A.
Poon, M. C.
Pu, W. T.
Putt, M. E.
Rabi, A.
Ralston, J.
Rey, S.
Rickter, E.
Rosen, B. R.
Runge, A.
Russell, D. W.
Sarkar, K.
Savino, L.
Schaper, W.
Schmidt-Neilsen, K.
Schmitz-Rixen, T.
Scholz, D.
Semenza, G. L.
Shaked, Y.
Shin, D. B.
Silver, M.
Simon, M. C.
Skuli, N.
Solonenko, M.
Sowers, A. L.
Spencer, D. M.
Spray, T. L.
Steadman, J. M.
Stewart, C.
Stott, J. J.
Strangman, G.
Strazza, M.
Subramanian, S.
Swartz, H. M.
Takatani, S.
Tian, H.
Trigg, N. J.
Tulip, J.
van Royen, N.
Vandiver, S.
Vogel, S.
Vulcan, T.
Wagner, S.
Wang, G. L.
Wang, H. W.
Wang, H.-W.
Wang, J. J.
Wang, T.
Wesley, J. B.
Wileyto, E. P.
Winter, S. F.
Witzenbichler, B.
Wolf, R. L.
Wolfram, S.
Yodh, A.
Yodh, A. G.
Yu, G.
Yu, G. Q.
Yuan, L.
Yuan, M.
Zhang, H.
Zheng, L. P.
Zheng, Y.
Zhou, B.
Zhou, C.
Zhou, Y. F.
Zhu, T. C.
Ziegelhoeffer, T.
Zimmerman, R. A.
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
- S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992). [CrossRef] [PubMed]
- T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010). [CrossRef]
- J. A. Bertout, S. A. Patel, and M. C. Simon, “The impact of O2 availability on human cancer,” Nat. Rev. Cancer 8(12), 967–975 (2008). [CrossRef] [PubMed]
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- D. A. Boas, J. P. Culver, J. J. Stott, and A. K. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head,” Opt. Express 10(3), 159–170 (2002). [PubMed]
- D. A. Boas and A. G. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997). [CrossRef]
- D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- K. R. Forrester, C. Stewart, J. Tulip, C. Leonard, and R. C. Bray, “Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue,” Med. Biol. Eng. Comput. 40(6), 687–697 (2002). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovasc. Res. 49(3), 609–617 (2001). [CrossRef] [PubMed]
- D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995). [CrossRef] [PubMed]
- P. Carmeliet, “Angiogenesis in life, disease and medicine,” Nature 438(7070), 932–936 (2005). [CrossRef] [PubMed]
- P. Carmeliet, “Mechanisms of angiogenesis and arteriogenesis,” Nat. Med. 6(4), 389–395 (2000). [CrossRef] [PubMed]
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010). [CrossRef]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992). [CrossRef] [PubMed]
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
- K. L. Covello and M. C. Simon, “HIFs, hypoxia, and vascular development,” Curr. Top. Dev. Biol. 62, 37–54 (2004). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
- D. A. Boas, J. P. Culver, J. J. Stott, and A. K. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head,” Opt. Express 10(3), 159–170 (2002). [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- G. Q. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI,” Opt. Express 15(3), 1064–1075 (2007). [CrossRef] [PubMed]
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010). [CrossRef]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- G. Q. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI,” Opt. Express 15(3), 1064–1075 (2007). [CrossRef] [PubMed]
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- M. Heil, I. Eitenmüller, T. Schmitz-Rixen, and W. Schaper, “Arteriogenesis versus angiogenesis: similarities and differences,” J. Cell. Mol. Med. 10(1), 45–55 (2006). [CrossRef] [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- K. R. Forrester, C. Stewart, J. Tulip, C. Leonard, and R. C. Bray, “Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue,” Med. Biol. Eng. Comput. 40(6), 687–697 (2002). [CrossRef] [PubMed]
- V. E. Papaioannou and J. G. Fox, “Efficacy of tribromoethanol anesthesia in mice,” Lab. Anim. Sci. 43(2), 189–192 (1993). [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- S. Takatani and M. D. Graham, “Theoretical analysis of diffuse reflectance from a two-layer tissue model,” IEEE Trans. Biomed. Eng. 26(12), 656–664 (1979). [CrossRef] [PubMed]
- L. H. Gray and J. M. Steadman, “Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood,” J. Physiol. 175, 161–171 (1964). [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- B. Zhou, M. C. Poon, W. T. Pu, and Z. C. Han, “Therapeutic neovascularization for peripheral arterial diseases: advances and perspectives,” Histol. Histopathol. 22(6), 677–686 (2007). [PubMed]
- M. Heil, I. Eitenmüller, T. Schmitz-Rixen, and W. Schaper, “Arteriogenesis versus angiogenesis: similarities and differences,” J. Cell. Mol. Med. 10(1), 45–55 (2006). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- M. M. Hickey and M. C. Simon, “Regulation of angiogenesis by hypoxia and hypoxia-inducible factors,” Curr. Top. Dev. Biol. 76, 217–257 (2006). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovasc. Res. 49(3), 609–617 (2001). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- K. Schmidt-Neilsen and J. L. Larimer, “Oxygen dissociation curves of mammalian blood in relation to body size,” Am. J. Physiol. 195(2), 424–428 (1958). [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- K. R. Forrester, C. Stewart, J. Tulip, C. Leonard, and R. C. Bray, “Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue,” Med. Biol. Eng. Comput. 40(6), 687–697 (2002). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- H. Tian, S. L. McKnight, and D. W. Russell, “Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells,” Genes Dev. 11(1), 72–82 (1997). [CrossRef] [PubMed]
- J. A. Nelder and R. Mead, “A simplex method for function minimization,” Comput. J. 7, 308–313 (1965).
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
- J. A. Nelder and R. Mead, “A simplex method for function minimization,” Comput. J. 7, 308–313 (1965).
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- V. E. Papaioannou and J. G. Fox, “Efficacy of tribromoethanol anesthesia in mice,” Lab. Anim. Sci. 43(2), 189–192 (1993). [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- J. A. Bertout, S. A. Patel, and M. C. Simon, “The impact of O2 availability on human cancer,” Nat. Rev. Cancer 8(12), 967–975 (2008). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovasc. Res. 49(3), 609–617 (2001). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- B. Zhou, M. C. Poon, W. T. Pu, and Z. C. Han, “Therapeutic neovascularization for peripheral arterial diseases: advances and perspectives,” Histol. Histopathol. 22(6), 677–686 (2007). [PubMed]
- B. Zhou, M. C. Poon, W. T. Pu, and Z. C. Han, “Therapeutic neovascularization for peripheral arterial diseases: advances and perspectives,” Histol. Histopathol. 22(6), 677–686 (2007). [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- H. Tian, S. L. McKnight, and D. W. Russell, “Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells,” Genes Dev. 11(1), 72–82 (1997). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
- W. Schaper, “Collateral circulation: past and present,” Basic Res. Cardiol. 104(1), 5–21 (2009). [CrossRef] [PubMed]
- M. Heil, I. Eitenmüller, T. Schmitz-Rixen, and W. Schaper, “Arteriogenesis versus angiogenesis: similarities and differences,” J. Cell. Mol. Med. 10(1), 45–55 (2006). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovasc. Res. 49(3), 609–617 (2001). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- K. Schmidt-Neilsen and J. L. Larimer, “Oxygen dissociation curves of mammalian blood in relation to body size,” Am. J. Physiol. 195(2), 424–428 (1958). [PubMed]
- M. Heil, I. Eitenmüller, T. Schmitz-Rixen, and W. Schaper, “Arteriogenesis versus angiogenesis: similarities and differences,” J. Cell. Mol. Med. 10(1), 45–55 (2006). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- G. L. Wang and G. L. Semenza, “Purification and characterization of hypoxia-inducible factor 1,” J. Biol. Chem. 270(3), 1230–1237 (1995). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- J. A. Bertout, S. A. Patel, and M. C. Simon, “The impact of O2 availability on human cancer,” Nat. Rev. Cancer 8(12), 967–975 (2008). [CrossRef] [PubMed]
- M. M. Hickey and M. C. Simon, “Regulation of angiogenesis by hypoxia and hypoxia-inducible factors,” Curr. Top. Dev. Biol. 76, 217–257 (2006). [CrossRef] [PubMed]
- K. L. Covello and M. C. Simon, “HIFs, hypoxia, and vascular development,” Curr. Top. Dev. Biol. 62, 37–54 (2004). [CrossRef] [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- L. H. Gray and J. M. Steadman, “Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood,” J. Physiol. 175, 161–171 (1964). [PubMed]
- K. R. Forrester, C. Stewart, J. Tulip, C. Leonard, and R. C. Bray, “Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue,” Med. Biol. Eng. Comput. 40(6), 687–697 (2002). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- S. Takatani and M. D. Graham, “Theoretical analysis of diffuse reflectance from a two-layer tissue model,” IEEE Trans. Biomed. Eng. 26(12), 656–664 (1979). [CrossRef] [PubMed]
- H. Tian, S. L. McKnight, and D. W. Russell, “Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells,” Genes Dev. 11(1), 72–82 (1997). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- K. R. Forrester, C. Stewart, J. Tulip, C. Leonard, and R. C. Bray, “Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue,” Med. Biol. Eng. Comput. 40(6), 687–697 (2002). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovasc. Res. 49(3), 609–617 (2001). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- G. L. Wang and G. L. Semenza, “Purification and characterization of hypoxia-inducible factor 1,” J. Biol. Chem. 270(3), 1230–1237 (1995). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- G. Q. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI,” Opt. Express 15(3), 1064–1075 (2007). [CrossRef] [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010). [CrossRef]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- G. Q. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI,” Opt. Express 15(3), 1064–1075 (2007). [CrossRef] [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- D. A. Boas and A. G. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997). [CrossRef]
- D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
- B. Zhou, M. C. Poon, W. T. Pu, and Z. C. Han, “Therapeutic neovascularization for peripheral arterial diseases: advances and perspectives,” Histol. Histopathol. 22(6), 677–686 (2007). [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- G. Q. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI,” Opt. Express 15(3), 1064–1075 (2007). [CrossRef] [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
Am. J. Pathol.
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
Am. J. Physiol.
- K. Schmidt-Neilsen and J. L. Larimer, “Oxygen dissociation curves of mammalian blood in relation to body size,” Am. J. Physiol. 195(2), 424–428 (1958). [PubMed]
Arterioscler. Thromb. Vasc. Biol.
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
Basic Res. Cardiol.
- W. Schaper, “Collateral circulation: past and present,” Basic Res. Cardiol. 104(1), 5–21 (2009). [CrossRef] [PubMed]
Blood
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
Cancer Res.
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
Cardiovasc. Res.
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovasc. Res. 49(3), 609–617 (2001). [CrossRef] [PubMed]
Circ. Res.
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
Comput. J.
- J. A. Nelder and R. Mead, “A simplex method for function minimization,” Comput. J. 7, 308–313 (1965).
Curr. Top. Dev. Biol.
- M. M. Hickey and M. C. Simon, “Regulation of angiogenesis by hypoxia and hypoxia-inducible factors,” Curr. Top. Dev. Biol. 76, 217–257 (2006). [CrossRef] [PubMed]
- K. L. Covello and M. C. Simon, “HIFs, hypoxia, and vascular development,” Curr. Top. Dev. Biol. 62, 37–54 (2004). [CrossRef] [PubMed]
Genes Dev.
- H. Tian, S. L. McKnight, and D. W. Russell, “Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells,” Genes Dev. 11(1), 72–82 (1997). [CrossRef] [PubMed]
Histol. Histopathol.
- B. Zhou, M. C. Poon, W. T. Pu, and Z. C. Han, “Therapeutic neovascularization for peripheral arterial diseases: advances and perspectives,” Histol. Histopathol. 22(6), 677–686 (2007). [PubMed]
IEEE Trans. Biomed. Eng.
- S. Takatani and M. D. Graham, “Theoretical analysis of diffuse reflectance from a two-layer tissue model,” IEEE Trans. Biomed. Eng. 26(12), 656–664 (1979). [CrossRef] [PubMed]
J. Biol. Chem.
- G. L. Wang and G. L. Semenza, “Purification and characterization of hypoxia-inducible factor 1,” J. Biol. Chem. 270(3), 1230–1237 (1995). [CrossRef] [PubMed]
J. Biomed. Opt.
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
J. Cell. Mol. Med.
- M. Heil, I. Eitenmüller, T. Schmitz-Rixen, and W. Schaper, “Arteriogenesis versus angiogenesis: similarities and differences,” J. Cell. Mol. Med. 10(1), 45–55 (2006). [CrossRef] [PubMed]
J. Cereb. Blood Flow Metab.
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
J. Mol. Cell. Cardiol.
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
J. Opt. Soc. Am. A
- D. A. Boas and A. G. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997). [CrossRef]
J. Physiol.
- L. H. Gray and J. M. Steadman, “Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood,” J. Physiol. 175, 161–171 (1964). [PubMed]
Lab. Anim. Sci.
- V. E. Papaioannou and J. G. Fox, “Efficacy of tribromoethanol anesthesia in mice,” Lab. Anim. Sci. 43(2), 189–192 (1993). [PubMed]
Magn. Reson. Med.
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
Med. Biol. Eng. Comput.
- K. R. Forrester, C. Stewart, J. Tulip, C. Leonard, and R. C. Bray, “Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue,” Med. Biol. Eng. Comput. 40(6), 687–697 (2002). [CrossRef] [PubMed]
Nat. Med.
- P. Carmeliet, “Mechanisms of angiogenesis and arteriogenesis,” Nat. Med. 6(4), 389–395 (2000). [CrossRef] [PubMed]
Nat. Protoc.
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
Nat. Rev. Cancer
- J. A. Bertout, S. A. Patel, and M. C. Simon, “The impact of O2 availability on human cancer,” Nat. Rev. Cancer 8(12), 967–975 (2008). [CrossRef] [PubMed]
Nature
- P. Carmeliet, “Angiogenesis in life, disease and medicine,” Nature 438(7070), 932–936 (2005). [CrossRef] [PubMed]
Neurocrit. Care
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
Neuroimage
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
Oncogene
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
Opt. Express
- G. Q. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI,” Opt. Express 15(3), 1064–1075 (2007). [CrossRef] [PubMed]
- D. A. Boas, J. P. Culver, J. J. Stott, and A. K. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head,” Opt. Express 10(3), 159–170 (2002). [PubMed]
- L. Gagnon, M. Desjardins, J. Jehanne-Lacasse, L. Bherer, and F. Lesage, “Investigation of diffuse correlation spectroscopy in multi-layered media including the human head,” Opt. Express 16(20), 15514–15530 (2008). [CrossRef] [PubMed]
Photochem. Photobiol.
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
Phys. Med. Biol.
- S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
Phys. Rev. Lett.
- D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995). [CrossRef] [PubMed]
Rep. Prog. Phys.
- T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010). [CrossRef]
Other
- S. Prahl, Optical properties spectra, http://omlc.ogi.edu/spectra/index.html
2010, Durduran, Rep. Prog. Phys.
- T. Durduran, R. Choe, W. B. Baker, and A. G. Yodh, “Diffuse optics for tissue monitoring and tomography,” Rep. Prog. Phys. 73(7), 076701 (2010). [CrossRef]
- T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht, “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J. Biomed. Opt. 15(3), 037004 (2010). [CrossRef] [PubMed]
- M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, “Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults,” Neurocrit. Care 12(2), 173–180 (2010). [CrossRef] [PubMed]
- C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J. Biomed. Opt. 14(3), 034015 (2009). [CrossRef] [PubMed]
- N. Skuli, L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith, “Endothelial deletion of hypoxia-inducible factor-2 (HIF-2 ) alters vascular function and tumor angiogenesis,” Blood 114(2), 469–477 (2009). [CrossRef] [PubMed]
- A. Limbourg, T. Korff, L. C. Napp, W. Schaper, H. Drexler, and F. P. Limbourg, “Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia,” Nat. Protoc. 4(12), 1737–1748 (2009). [CrossRef] [PubMed]
- W. Schaper, “Collateral circulation: past and present,” Basic Res. Cardiol. 104(1), 5–21 (2009). [CrossRef] [PubMed]
- J. A. Bertout, S. A. Patel, and M. C. Simon, “The impact of O2 availability on human cancer,” Nat. Rev. Cancer 8(12), 967–975 (2008). [CrossRef] [PubMed]
- B. Zhou, M. C. Poon, W. T. Pu, and Z. C. Han, “Therapeutic neovascularization for peripheral arterial diseases: advances and perspectives,” Histol. Histopathol. 22(6), 677–686 (2007). [PubMed]
- M. Bosch-Marce, H. Okuyama, J. B. Wesley, K. Sarkar, H. Kimura, Y. V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y. F. Zhou, K. R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G. L. Semenza, “Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia,” Circ. Res. 101(12), 1310–1318 (2007). [CrossRef] [PubMed]
- H.-W. Wang, E. Rickter, M. Yuan, E. P. Wileyto, E. Glatstein, A. Yodh, and T. M. Busch*, “Effect of Photosensitizer Dose on Fluence Rate Responses to Photodynamic Therapy,” Photochem. Photobiol. 83(5), 1040–1048 (2007). [CrossRef] [PubMed]
- H. W. Wang, J. C. Finlay, K. Lee, T. C. Zhu, M. E. Putt, E. Glatstein, C. J. Koch, S. M. Evans, S. M. Hahn, T. M. Busch, and A. G. Yodh, “Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis,” J. Biomed. Opt. 12(3), 034023 (2007). [CrossRef] [PubMed]
- S. F. Winter, V. D. Acevedo, R. D. Gangula, K. W. Freeman, D. M. Spencer, and N. M. Greenberg, “Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2,” Oncogene 26(34), 4897–4907 (2007). [CrossRef] [PubMed]
- M. M. Hickey and M. C. Simon, “Regulation of angiogenesis by hypoxia and hypoxia-inducible factors,” Curr. Top. Dev. Biol. 76, 217–257 (2006). [CrossRef] [PubMed]
- M. Heil, I. Eitenmüller, T. Schmitz-Rixen, and W. Schaper, “Arteriogenesis versus angiogenesis: similarities and differences,” J. Cell. Mol. Med. 10(1), 45–55 (2006). [CrossRef] [PubMed]
- A. Helisch, S. Wagner, N. Khan, M. Drinane, S. Wolfram, M. Heil, T. Ziegelhoeffer, U. Brandt, J. D. Pearlman, H. M. Swartz, and W. Schaper, “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arterioscler. Thromb. Vasc. Biol. 26(3), 520–526 (2005). [CrossRef] [PubMed]
- P. Carmeliet, “Angiogenesis in life, disease and medicine,” Nature 438(7070), 932–936 (2005). [CrossRef] [PubMed]
- A. Matsumoto, S. Matsumoto, A. L. Sowers, J. W. Koscielniak, N. J. Trigg, P. Kuppusamy, J. B. Mitchell, S. Subramanian, M. C. Krishna, and K. I. Matsumoto, “Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR,” Magn. Reson. Med. 54(6), 1530–1535 (2005). [CrossRef] [PubMed]
- H. W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh, and T. M. Busch, “Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res. 64(20), 7553–7561 (2004). [CrossRef] [PubMed]
- K. L. Covello and M. C. Simon, “HIFs, hypoxia, and vascular development,” Curr. Top. Dev. Biol. 62, 37–54 (2004). [CrossRef] [PubMed]
- J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia,” J. Cereb. Blood Flow Metab. 23(8), 911–924 (2003). [CrossRef] [PubMed]
- D. A. Boas, G. Strangman, J. P. Culver, R. D. Hoge, G. Jasdzewski, R. A. Poldrack, B. R. Rosen, and J. B. Mandeville, “Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?” Phys. Med. Biol. 48(15), 2405–2418 (2003). [CrossRef] [PubMed]
- D. Scholz, T. Ziegelhoeffer, A. Helisch, S. Wagner, C. Friedrich, T. Podzuweit, and W. Schaper, “Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice,” J. Mol. Cell. Cardiol. 34(7), 775–787 (2002). [CrossRef] [PubMed]
- K. R. Forrester, C. Stewart, J. Tulip, C. Leonard, and R. C. Bray, “Comparison of laser speckle and laser Doppler perfusion imaging: measurement in human skin and rabbit articular tissue,” Med. Biol. Eng. Comput. 40(6), 687–697 (2002). [CrossRef] [PubMed]
- M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn, and A. G. Yodh, “In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates,” Phys. Med. Biol. 47(6), 857–873 (2002). [PubMed]
- E. Deindl, I. Buschmann, I. E. Hoefer, T. Podzuweit, K. Boengler, S. Vogel, N. van Royen, B. Fernandez, and W. Schaper, “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circ. Res. 89(9), 779–786 (2001). [CrossRef] [PubMed]
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovasc. Res. 49(3), 609–617 (2001). [CrossRef] [PubMed]
- J. Mayhew, D. Johnston, J. Martindale, M. Jones, J. Berwick, and Y. Zheng, “Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex,” Neuroimage 13(6), 975–987 (2001). [CrossRef] [PubMed]
- P. Carmeliet, “Mechanisms of angiogenesis and arteriogenesis,” Nat. Med. 6(4), 389–395 (2000). [CrossRef] [PubMed]
- T. Couffinhal, M. Silver, L. P. Zheng, M. Kearney, B. Witzenbichler, and J. M. Isner, “Mouse model of angiogenesis,” Am. J. Pathol. 152(6), 1667–1679 (1998). [PubMed]
- H. Tian, S. L. McKnight, and D. W. Russell, “Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells,” Genes Dev. 11(1), 72–82 (1997). [CrossRef] [PubMed]
- G. L. Wang and G. L. Semenza, “Purification and characterization of hypoxia-inducible factor 1,” J. Biol. Chem. 270(3), 1230–1237 (1995). [CrossRef] [PubMed]
- D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and imaging with diffusing temporal field correlations,” Phys. Rev. Lett. 75(9), 1855–1858 (1995). [CrossRef] [PubMed]
- V. E. Papaioannou and J. G. Fox, “Efficacy of tribromoethanol anesthesia in mice,” Lab. Anim. Sci. 43(2), 189–192 (1993). [PubMed]
- S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys. Med. Biol. 37(7), 1531–1560 (1992). [CrossRef] [PubMed]
- S. Takatani and M. D. Graham, “Theoretical analysis of diffuse reflectance from a two-layer tissue model,” IEEE Trans. Biomed. Eng. 26(12), 656–664 (1979). [CrossRef] [PubMed]
- J. A. Nelder and R. Mead, “A simplex method for function minimization,” Comput. J. 7, 308–313 (1965).
- L. H. Gray and J. M. Steadman, “Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood,” J. Physiol. 175, 161–171 (1964). [PubMed]
- K. Schmidt-Neilsen and J. L. Larimer, “Oxygen dissociation curves of mammalian blood in relation to body size,” Am. J. Physiol. 195(2), 424–428 (1958). [PubMed]
Cited By |
 Alert me when this paper is cited |
OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.
Related Journal Articles 
- Three-dimensional tomographic reconstruction of an absorptive perturbation with diffuse photon density waves (JOSAA)
- Theory of a fixed scatterer embedded in a turbid medium: numerical results (JOSAA)
- Simulation of scanning laser techniques for optical imaging of blood-related intrinsic signals (JOSAA)
- Light-scattering properties of undiluted human blood subjected to simple shear (JOSAA)
- Delayed Luminescence of Biophotons from Plant Leaves (JOSK)
Related Conference Papers
- CLEO Tutorial: Microfluidic large scale integration
- Simulation of 3D light propagation in a layered head model including a clear CSF layer
- Reconstructed images for oxy and deoxy hemoglobin for a phantom with varied local oxygenation using optical CT
- Analysis of a 3-D tumor localization algorithm from a single 2-D measurement using diffraction tomography
- The Fourier diffraction theorem for turbid media
« Previous Article | Next Article »
OSA is a member of 
For optimal display we recommend the following web browsers:
- Firefox 11+
- Google Chrome 17+
- Internet Explorer 9+
- Safari 5+