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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 11 — Nov. 1, 2011
  • pp: 3037–3046

Micrometer axial resolution OCT for corneal imaging

Rahul Yadav, Kye-Sung Lee, Jannick P. Rolland, James M. Zavislan, James V. Aquavella, and Geunyoung Yoon  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 11, pp. 3037-3046 (2011)
http://dx.doi.org/10.1364/BOE.2.003037


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Abstract

An optical coherence tomography (OCT) for high axial resolution corneal imaging is presented. The system uses 375 nm bandwidth (625 to 1000 nm) from a broadband supercontinuum light source. The system was developed in free space to minimize image quality degradation due to dispersion. A custom-designed spectrometer based on a Czerny Turner configuration was implemented to achieve an imaging depth of 1 mm. Experimentally measured axial resolution was 1.1 μm in corneal tissue and had a good agreement with the theoretically calculated resolution from the envelope of the spectral interference fringes. In vivo imaging was carried out and thin corneal layers such as the tear film and the Bowman’s layer were quantified in normal, keratoconus, and contact lens wearing eyes, indicating the system’s suitability for several ophthalmic applications.

© 2011 OSA

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Ophthalmology Applications

History
Original Manuscript: June 23, 2011
Revised Manuscript: September 10, 2011
Manuscript Accepted: October 4, 2011
Published: October 6, 2011

Citation
Rahul Yadav, Kye-Sung Lee, Jannick P. Rolland, James M. Zavislan, James V. Aquavella, and Geunyoung Yoon, "Micrometer axial resolution OCT for corneal imaging," Biomed. Opt. Express 2, 3037-3046 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-11-3037


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