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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 12 — Dec. 1, 2011
  • pp: 3367–3386

Spatiotemporal relations of primary sensorimotor and secondary motor activation patterns mapped by NIR imaging

Bilal Khan, Pankaj Chand, and George Alexandrakis  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 12, pp. 3367-3386 (2011)
http://dx.doi.org/10.1364/BOE.2.003367


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Abstract

Functional near infrared (fNIR) imaging was used to identify spatiotemporal relations between spatially distinct cortical regions activated during various hand and arm motion protocols. Imaging was performed over a field of view (FOV, 12 x 8.4 cm) including the secondary motor, primary sensorimotor, and the posterior parietal cortices over a single brain hemisphere. This is a more extended FOV than typically used in current fNIR studies. Three subjects performed four motor tasks that induced activation over this extended FOV. The tasks included card flipping (pronation and supination) that, to our knowledge, has not been performed in previous functional magnetic resonance imaging (fMRI) or fNIR studies. An earlier rise and a longer duration of the hemodynamic activation response were found in tasks requiring increased physical or mental effort. Additionally, analysis of activation images by cluster component analysis (CCA) demonstrated that cortical regions can be grouped into clusters, which can be adjacent or distant from each other, that have similar temporal activation patterns depending on whether the performed motor task is guided by visual or tactile feedback. These analyses highlight the future potential of fNIR imaging to tackle clinically relevant questions regarding the spatiotemporal relations between different sensorimotor cortex regions, e.g. ones involved in the rehabilitation response to motor impairments.

© 2011 OSA

OCIS Codes
(100.2960) Image processing : Image analysis
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(300.6340) Spectroscopy : Spectroscopy, infrared
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Neuroscience and Brain Imaging

History
Original Manuscript: July 7, 2011
Revised Manuscript: September 20, 2011
Manuscript Accepted: November 16, 2011
Published: November 29, 2011

Citation
Bilal Khan, Pankaj Chand, and George Alexandrakis, "Spatiotemporal relations of primary sensorimotor and secondary motor activation patterns mapped by NIR imaging," Biomed. Opt. Express 2, 3367-3386 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-12-3367


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