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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 3 — Mar. 1, 2011
  • pp: 421–430

Novel focused OCT-LIF endoscope

R. Andrew Wall, Garret T. Bonnema, and Jennifer K. Barton  »View Author Affiliations

Biomedical Optics Express, Vol. 2, Issue 3, pp. 421-430 (2011)

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Combined optical coherence tomography (OCT) and laser-induced fluorescence (LIF) endoscopy has shown higher sensitivity and specificity for distinguishing normal tissue from adenoma when compared to either modality alone. Endoscope optical design is complicated by the large wavelength difference between the two systems. A new high-resolution endoscope 2 mm in diameter is presented that can create focused beams from the ultraviolet to near-infrared. A reflective design ball lens operates achromatically over a large wavelength range, and employs TIR at two faces and reflection at a third internal mirrored face. The 1:1 imaging system obtains theoretically diffraction-limited spots for both the OCT (1300 nm) and LIF (325 nm) channels.

© 2011 OSA

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.2680) Medical optics and biotechnology : Gastrointestinal
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence

ToC Category:
Endoscopes, Catheters and Micro-Optics

Original Manuscript: September 14, 2010
Revised Manuscript: November 4, 2010
Manuscript Accepted: January 28, 2011
Published: January 31, 2011

R. Andrew Wall, Garret T. Bonnema, and Jennifer K. Barton, "Novel focused OCT-LIF endoscope," Biomed. Opt. Express 2, 421-430 (2011)

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