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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 3 — Mar. 1, 2011
  • pp: 658–664

Optofluidic lab-on-a-chip for rapid algae population screening

Allison Schaap, Yves Bellouard, and Thomas Rohrlack  »View Author Affiliations

Biomedical Optics Express, Vol. 2, Issue 3, pp. 658-664 (2011)

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The rapid identification of algae species is not only of practical importance when monitoring unwanted adverse effects such as eutrophication, but also when assessing the water quality of watersheds. Here, we demonstrate a lab-on-a-chip that functions as a compact robust tool for the fast screening, real-time monitoring, and initial classification of algae. The water-algae sample, flowing in a microfluidic channel, is side-illuminated by an integrated subsurface waveguide. The waveguide is curved to improve the device sensitivity. The changes in the transmitted optical signal are monitored using a quadrant-cell photo-detector. The signal-wavelets from the different quadrants are used to qualitatively distinguish different families of algae. The channel and waveguide are fabricated out of a monolithic fused-silica substrate using a femtosecond laser-writing process combined with chemical etching. This proof-of-concept device paves the way for more elaborate femtosecond laser-based optofluidic micro-instruments incorporating waveguide networks designed for the real-time field analysis of cells and microorganisms.

© 2011 OSA

OCIS Codes
(130.3120) Integrated optics : Integrated optics devices
(130.6010) Integrated optics : Sensors
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(130.2755) Integrated optics : Glass waveguides
(130.3990) Integrated optics : Micro-optical devices

ToC Category:

Original Manuscript: January 21, 2011
Revised Manuscript: February 16, 2011
Manuscript Accepted: February 16, 2011
Published: February 23, 2011

Allison Schaap, Yves Bellouard, and Thomas Rohrlack, "Optofluidic lab-on-a-chip for rapid algae population screening," Biomed. Opt. Express 2, 658-664 (2011)

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