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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 5 — May. 1, 2011
  • pp: 1097–1105

Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.

Donald C. Hood and Ali S. Raza  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 5, pp. 1097-1105 (2011)
http://dx.doi.org/10.1364/BOE.2.001097


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Abstract

To relate structural (anatomical) and functional (behavioral) measures of glaucomatous damage, a method is described for comparing visual field defects to local retinal ganglion cell (RGC) and retinal nerve fiber layer (RNFL) thicknesses. Thickness maps of the RNFL and the RGC + inner plexiform layer, obtained with frequency domain optical coherence tomography (fdOCT), were transformed into probability maps by comparing them to a normative group. As demonstrated in patients with glaucomatous damage to the macula, the probability map associated with the patient’s visual field can be directly compared to the fdOCT probability maps by taking into consideration the displacement of the RGCs.

© 2011 OSA

OCIS Codes
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(330.4300) Vision, color, and visual optics : Vision system - noninvasive assessment

ToC Category:
Ophthalmology Applications

History
Original Manuscript: February 25, 2011
Revised Manuscript: March 28, 2011
Manuscript Accepted: March 28, 2011
Published: April 5, 2011

Virtual Issues
Cellular Imaging of the Retina (2011) Biomedical Optics Express

Citation
Donald C. Hood and Ali S. Raza, "Method for comparing visual field defects to local RNFL and RGC damage seen on frequency domain OCT in patients with glaucoma.," Biomed. Opt. Express 2, 1097-1105 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-5-1097


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References

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