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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 5 — May. 1, 2011
  • pp: 1147–1158

Enhanced imaging of choroidal vasculature by high-penetration and dual-velocity optical coherence angiography

Franck Jaillon, Shuichi Makita, Eun-Jung Min, Byeong Ha Lee, and Yoshiaki Yasuno  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 5, pp. 1147-1158 (2011)
http://dx.doi.org/10.1364/BOE.2.001147


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Abstract

Dual-beam-scan Doppler optical coherence angiography (DB-OCA) with a 1-μm-wavelength probe is demonstrated for improved in vivo choroidal angiograms of the human eye. This method utilizes two scanning beams with spatial and temporal separation on the retina, and provides two measurable velocity ranges. The method achieves higher sensitivity to very low velocity flows than conventional Doppler optical coherence tomography. Moreover, longer wavelengths allowing greater penetration, enhanced visualization of choroidal vessels is verified with en-face projection images of the Doppler shift squared. Specifically, better choroidal vasculature visibility is achieved at a wavelength of 1 μm than at 840 nm.

© 2011 OSA

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Ophthalmology Applications

History
Original Manuscript: March 1, 2011
Revised Manuscript: April 6, 2011
Manuscript Accepted: April 6, 2011
Published: April 11, 2011

Virtual Issues
In vivo Microcirculation Imaging (2011) Biomedical Optics Express

Citation
Franck Jaillon, Shuichi Makita, Eun-Jung Min, Byeong Ha Lee, and Yoshiaki Yasuno, "Enhanced imaging of choroidal vasculature by high-penetration and dual-velocity optical coherence angiography," Biomed. Opt. Express 2, 1147-1158 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-5-1147


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