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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 6 — Jun. 1, 2011
  • pp: 1734–1742

Deriving visual field loss based upon OCT of inner retinal thicknesses of the macula

Xian Zhang, Corey J. Bregman, Ali S. Raza, C. Gustavo De Moraes, and Donald C. Hood  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 6, pp. 1734-1742 (2011)
http://dx.doi.org/10.1364/BOE.2.001734


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Abstract

Using a multiple linear regression method, a derived visual field (VF) was obtained from retinal ganglion cell and retinal nerve fiber layer (RNFL) thicknesses measured with frequency-domain, optical coherence tomography (OCT) macular scans. 138 eyes from 92 glaucoma patients or suspects and 58 healthy eyes were included. The derived VF was compared to the VF measured with standard automated perimetry (SAP). The median agreement between the derived and observed VFs was 90%. As the derived and observed VFs should be independent, they can be combined to potentially increase the sensitivity/specificity of a test for glaucoma.

© 2011 OSA

OCIS Codes
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(330.4300) Vision, color, and visual optics : Vision system - noninvasive assessment

ToC Category:
Vision, Color, and Visual Optics

History
Original Manuscript: February 25, 2011
Revised Manuscript: May 20, 2011
Manuscript Accepted: May 25, 2011
Published: May 26, 2011

Citation
Xian Zhang, Corey J. Bregman, Ali S. Raza, C. Gustavo De Moraes, and Donald C. Hood, "Deriving visual field loss based upon OCT of inner retinal thicknesses of the macula," Biomed. Opt. Express 2, 1734-1742 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-6-1734


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References

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