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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 7 — Jul. 1, 2011
  • pp: 1781–1793

Off-axis quantitative phase imaging processing using CUDA: toward real-time applications

Hoa Pham, Huafeng Ding, Nahil Sobh, Minh Do, Sanjay Patel, and Gabriel Popescu  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 7, pp. 1781-1793 (2011)
http://dx.doi.org/10.1364/BOE.2.001781


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Abstract

We demonstrate real time off-axis Quantitative Phase Imaging (QPI) using a phase reconstruction algorithm based on NVIDIA’s CUDA programming model. The phase unwrapping component is based on Goldstein’s algorithm. By mapping the process of extracting phase information and unwrapping to GPU, we are able to speed up the whole procedure by more than 18.8× with respect to CPU processing and ultimately achieve video rate for mega-pixel images. Our CUDA implementation also supports processing of multiple images simultaneously. This enables our imaging system to support high speed, high throughput, and real-time image acquisition and visualization.

© 2011 OSA

OCIS Codes
(100.5070) Image processing : Phase retrieval
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(180.3170) Microscopy : Interference microscopy
(100.5088) Image processing : Phase unwrapping

ToC Category:
Microscopy

History
Original Manuscript: April 14, 2011
Revised Manuscript: May 23, 2011
Manuscript Accepted: May 30, 2011
Published: June 1, 2011

Citation
Hoa Pham, Huafeng Ding, Nahil Sobh, Minh Do, Sanjay Patel, and Gabriel Popescu, "Off-axis quantitative phase imaging processing using CUDA: toward real-time applications," Biomed. Opt. Express 2, 1781-1793 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-7-1781


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References

  1. G. Popescu, in Methods in Cell Biology, B. P. Jena, ed. (Academic Press, San Diego, 2008), pp. 87–115.
  2. C. Depeursinge, “Digital holography applied to microscopy,” in Digital Holography and Three-Dimensional Display, T.-C. Poon, ed. (Springer, 2006), p. 98.
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