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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 9 — Sep. 1, 2011
  • pp: 2461–2469

Online object oriented Monte Carlo computational tool for the needs of biomedical optics

Alexander Doronin and Igor Meglinski  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 9, pp. 2461-2469 (2011)
http://dx.doi.org/10.1364/BOE.2.002461


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Abstract

Conceptual engineering design and optimization of laser-based imaging techniques and optical diagnostic systems used in the field of biomedical optics requires a clear understanding of the light-tissue interaction and peculiarities of localization of the detected optical radiation within the medium. The description of photon migration within the turbid tissue-like media is based on the concept of radiative transfer that forms a basis of Monte Carlo (MC) modeling. An opportunity of direct simulation of influence of structural variations of biological tissues on the probing light makes MC a primary tool for biomedical optics and optical engineering. Due to the diversity of optical modalities utilizing different properties of light and mechanisms of light-tissue interactions a new MC code is typically required to be developed for the particular diagnostic application. In current paper introducing an object oriented concept of MC modeling and utilizing modern web applications we present the generalized online computational tool suitable for the major applications in biophotonics. The computation is supported by NVIDEA CUDA Graphics Processing Unit providing acceleration of modeling up to 340 times.

© 2011 OSA

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.5280) Medical optics and biotechnology : Photon migration
(170.7050) Medical optics and biotechnology : Turbid media
(200.4960) Optics in computing : Parallel processing

ToC Category:
Optics of Tissue and Turbid Media

History
Original Manuscript: June 20, 2011
Revised Manuscript: July 22, 2011
Manuscript Accepted: July 22, 2011
Published: July 29, 2011

Citation
Alexander Doronin and Igor Meglinski, "Online object oriented Monte Carlo computational tool for the needs of biomedical optics," Biomed. Opt. Express 2, 2461-2469 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-9-2461


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