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Extended depth of focus adaptive optics spectral domain optical coherence tomographyKazuhiro Sasaki, Kazuhiro Kurokawa, Shuichi Makita, and Yoshiaki Yasuno »View Author Affiliations
Kazuhiro Sasaki,
Kazuhiro Kurokawa,
Shuichi Makita,
and Yoshiaki Yasuno*
Computational Optics Group in the University of Tsukuba, Tsukuba, Japan *Corresponding author: yasuno@optlab2.bk.tsukuba.ac.jp |
Biomedical Optics Express, Vol. 3, Issue 10, pp. 2353-2370 (2012)
http://dx.doi.org/10.1364/BOE.3.002353
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Abstract
We present an adaptive optics spectral domain optical coherence tomography (AO-SDOCT) with a long focal range by active phase modulation of the pupil. A long focal range is achieved by introducing AO-controlled third-order spherical aberration (SA). The property of SA and its effects on focal range are investigated in detail using the Huygens-Fresnel principle, beam profile measurement and OCT imaging of a phantom. The results indicate that the focal range is extended by applying SA, and the direction of extension can be controlled by the sign of applied SA. Finally, we demonstrated in vivo human retinal imaging by altering the applied SA.
© 2012 OSA
OCIS Codes
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(110.1080) Imaging systems : Active or adaptive optics
ToC Category:
Optical Coherence Tomography
History
Original Manuscript: June 14, 2012
Revised Manuscript: August 6, 2012
Manuscript Accepted: August 29, 2012
Published: September 4, 2012
Virtual Issues
BIOMED 2012
(2012) Biomedical Optics Express
Citation
Kazuhiro Sasaki, Kazuhiro Kurokawa, Shuichi Makita, and Yoshiaki Yasuno, "Extended depth of focus adaptive optics spectral domain optical coherence
tomography," Biomed. Opt. Express 3, 2353-2370 (2012)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-3-10-2353
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References
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- R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, “Performance of fourier domain vs. time domain optical coherence tomography,” Opt. Express11(8), 889–894 (2003). [CrossRef] [PubMed]
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- E. J. Fernández, A. Unterhuber, B. Povazay, B. Hermann, P. Artal, and W. Drexler, “Chromatic aberration correction of the human eye for retinal imaging in the near infrared,” Opt. Express14(13), 6213–6225 (2006). [CrossRef] [PubMed]
- B. Hermann, E. J. Fernández, A. Unterhuber, H. Sattmann, A. F. Fercher, W. Drexler, P. M. Prieto, and P. Artal, “Adaptive-optics ultrahigh-resolution optical coherence tomography,” Opt. Lett.29(18), 2142–2144 (2004). [CrossRef] [PubMed]
- E. J. Fernández, I. Iglesias, and P. Artal, “Closed-loop adaptive optics in the human eye,” Opt. Lett.26(10), 746–748 (2001). [CrossRef] [PubMed]
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