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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 2 — Feb. 1, 2012
  • pp: 225–239

Adaptive optics with pupil tracking for high resolution retinal imaging

Betul Sahin, Barbara Lamory, Xavier Levecq, Fabrice Harms, and Chris Dainty  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 2, pp. 225-239 (2012)

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Adaptive optics, when integrated into retinal imaging systems, compensates for rapidly changing ocular aberrations in real time and results in improved high resolution images that reveal the photoreceptor mosaic. Imaging the retina at high resolution has numerous potential medical applications, and yet for the development of commercial products that can be used in the clinic, the complexity and high cost of the present research systems have to be addressed. We present a new method to control the deformable mirror in real time based on pupil tracking measurements which uses the default camera for the alignment of the eye in the retinal imaging system and requires no extra cost or hardware. We also present the first experiments done with a compact adaptive optics flood illumination fundus camera where it was possible to compensate for the higher order aberrations of a moving model eye and in vivo in real time based on pupil tracking measurements, without the real time contribution of a wavefront sensor. As an outcome of this research, we showed that pupil tracking can be effectively used as a low cost and practical adaptive optics tool for high resolution retinal imaging because eye movements constitute an important part of the ocular wavefront dynamics.

© 2012 OSA

OCIS Codes
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(100.4999) Image processing : Pattern recognition, target tracking
(110.1080) Imaging systems : Active or adaptive optics

ToC Category:
Active and Adaptive Optics

Original Manuscript: October 24, 2011
Revised Manuscript: December 19, 2011
Manuscript Accepted: December 21, 2011
Published: January 3, 2012

Betul Sahin, Barbara Lamory, Xavier Levecq, Fabrice Harms, and Chris Dainty, "Adaptive optics with pupil tracking for high resolution retinal imaging," Biomed. Opt. Express 3, 225-239 (2012)

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