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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 4 — Apr. 1, 2012
  • pp: 764–776

Seeing it through: translational validation of new medical imaging modalities

Melissa B. Aldrich, Milton V. Marshall, Eva M. Sevick-Muraca, Greg Lanza, John Kotyk, Joseph Culver, Lihong V. Wang, Jashim Uddin, Brenda C. Crews, Lawrence J. Marnett, Joseph C. Liao, Chris Contag, James M. Crawford, Ken Wang, Bill Reisdorph, Henry Appelman, D. Kim Turgeon, Charles Meyer, and Tom Wang  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 4, pp. 764-776 (2012)

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Medical imaging is an invaluable tool for diagnosis, surgical guidance, and assessment of treatment efficacy. The Network for Translational Research (NTR) for Optical Imaging consists of four research groups working to “bridge the gap” between lab discovery and clinical use of fluorescence- and photoacoustic-based imaging devices used with imaging biomarkers. While the groups are using different modalities, all the groups face similar challenges when attempting to validate these systems for FDA approval and, ultimately, clinical use. Validation steps taken, as well as future needs, are described here. The group hopes to provide translational validation guidance for itself, as well as other researchers.

© 2012 OSA

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Optics in Cancer Research

Original Manuscript: December 21, 2011
Revised Manuscript: February 10, 2012
Manuscript Accepted: February 13, 2012
Published: March 22, 2012

Melissa B. Aldrich, Milton V. Marshall, Eva M. Sevick-Muraca, Greg Lanza, John Kotyk, Joseph Culver, Lihong V. Wang, Jashim Uddin, Brenda C. Crews, Lawrence J. Marnett, Joseph C. Liao, Chris Contag, James M. Crawford, Ken Wang, Bill Reisdorph, Henry Appelman, D. Kim Turgeon, Charles Meyer, and Tom Wang, "Seeing it through: translational validation of new medical imaging modalities," Biomed. Opt. Express 3, 764-776 (2012)

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