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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 4 — Apr. 1, 2012
  • pp: 792–799

Near-infrared light photoacoustic ophthalmoscopy

Tan Liu, Qing Wei, Wei Song, Janice M. Burke, Shuliang Jiao, and Hao F. Zhang  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 4, pp. 792-799 (2012)

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We achieved photoacoustic ophthalmoscopy (PAOM) imaging of the retina with near-infrared (NIR) light illumination. A PAOM imaging system with dual-wavelength illumination at 1064 nm and 532 nm was built. We compared in vivo imaging results of both albino and pigmented rat eyes at the two wavelengths. The results show that the bulk optical absorption of the retinal pigment epithelium (RPE) is only slightly higher than that of the retinal vessels at 532 nm while it becomes more than an order of magnitude higher than that of the retinal vessels at 1064 nm. These studies suggest that although visible light illumination is suitable for imaging both the retinal vessels and the RPE, NIR light illumination, being more comfortable to the eye, is better suited for RPE melanin related investigations and diagnoses.

© 2012 OSA

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(170.4470) Medical optics and biotechnology : Ophthalmology

ToC Category:
Ophthalmology Applications

Original Manuscript: February 27, 2012
Manuscript Accepted: March 12, 2012
Published: March 27, 2012

Tan Liu, Qing Wei, Wei Song, Janice M. Burke, Shuliang Jiao, and Hao F. Zhang, "Near-infrared light photoacoustic ophthalmoscopy," Biomed. Opt. Express 3, 792-799 (2012)

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