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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 5 — May. 1, 2012
  • pp: 1110–1115

Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy

Euna Jung, Hyuck Jae Choi, Meehyun Lim, Hyeona Kang, Hongkyu Park, Haewook Han, Byung-hyun Min, Sangin Kim, Ikmo Park, and Hanjo Lim  »View Author Affiliations


Biomedical Optics Express, Vol. 3, Issue 5, pp. 1110-1115 (2012)
http://dx.doi.org/10.1364/BOE.3.001110


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Abstract

The water distribution in human osteoarthritic articular cartilage has been quantitatively characterized using terahertz time-domain spectroscopy (THz TDS). We measured the refractive index and absorption coefficient of cartilage tissue in the THz frequency range. Based on our measurements, the estimated water content was observed to decrease with increasing depth cartilage tissue, showing good agreement with a previous report based on destructive biochemical methods.

© 2012 OSA

OCIS Codes
(000.1430) General : Biology and medicine
(110.6795) Imaging systems : Terahertz imaging

ToC Category:
Spectroscopic Diagnostics

History
Original Manuscript: January 31, 2012
Revised Manuscript: March 14, 2012
Manuscript Accepted: March 14, 2012
Published: April 25, 2012

Citation
Euna Jung, Hyuck Jae Choi, Meehyun Lim, Hyeona Kang, Hongkyu Park, Haewook Han, Byung-hyun Min, Sangin Kim, Ikmo Park, and Hanjo Lim, "Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy," Biomed. Opt. Express 3, 1110-1115 (2012)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-3-5-1110


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