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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 5 — May. 1, 2012
  • pp: 920–926

Reusable molecular sensor based on photonic activation control of DNA probes

Takahiro Nishimura, Yusuke Ogura, and Jun Tanida  »View Author Affiliations


Biomedical Optics Express, Vol. 3, Issue 5, pp. 920-926 (2012)
http://dx.doi.org/10.1364/BOE.3.000920


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Abstract

We propose a photoactivatable and resettable molecular sensor using DNA probes. The functionality is achieved by reversible change of DNA structure induced via photonic signals. Based on the mechanism, the sensor can detect target molecules at a desired instant and can be returned to its initial state after detection. The experimental results demonstrate that the concentrations of the target molecules are detected correctly and repeatedly according to the light signal.

© 2012 OSA

OCIS Codes
(350.5130) Other areas of optics : Photochemistry
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Biosensors and Molecular Diagnostics

History
Original Manuscript: March 14, 2012
Revised Manuscript: April 3, 2012
Manuscript Accepted: April 4, 2012
Published: April 11, 2012

Citation
Takahiro Nishimura, Yusuke Ogura, and Jun Tanida, "Reusable molecular sensor based on photonic activation control of DNA probes," Biomed. Opt. Express 3, 920-926 (2012)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-3-5-920


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References

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