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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 6 — Jun. 1, 2012
  • pp: 1141–1148

Numerical comparison of X-ray differential phase contrast and attenuation contrast

Dieter Hahn, Pierre Thibault, Martin Bech, Marco Stockmar, Simone Schleede, Irene Zanette, Alexander Rack, Timm Weitkamp, Aniko Sztrókay, Thomas Schlossbauer, Fabian Bamberg, Maximilian Reiser, and Franz Pfeiffer  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 6, pp. 1141-1148 (2012)

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We present a numerical tool to compare directly the contrast-to-noise-ratio (CNR) of the attenuation- and differential phase-contrast signals available from grating-based X-ray imaging for single radiographs. The attenuation projection is differentiated to bring it into a modality comparable to the differential phase projection using a Gaussian derivative filter. A Relative Contrast Gain (RCG) is then defined as the ratio of the CNR of image values in a region of interest (ROI) in the differential phase projection to the CNR of image values in the same ROI in the differential attenuation projection. We apply the method on experimental data of human breast tissue acquired using a grating interferometer to compare the two contrast modes for two regions of interest differing in the type of tissue. Our results indicate that the proposed method can be used as a local estimate of the spatial distribution of the ratio δ/β, i.e., real and imaginary part of the complex refractive index, across a sample.

© 2012 OSA

OCIS Codes
(100.2000) Image processing : Digital image processing
(100.2960) Image processing : Image analysis
(110.7440) Imaging systems : X-ray imaging

ToC Category:
X-Ray Microscopy and Imaging

Original Manuscript: January 31, 2012
Revised Manuscript: March 14, 2012
Manuscript Accepted: March 14, 2012
Published: April 27, 2012

Dieter Hahn, Pierre Thibault, Martin Bech, Marco Stockmar, Simone Schleede, Irene Zanette, Alexander Rack, Timm Weitkamp, Aniko Sztrókay, Thomas Schlossbauer, Fabian Bamberg, Maximilian Reiser, and Franz Pfeiffer, "Numerical comparison of X-ray differential phase contrast and attenuation contrast," Biomed. Opt. Express 3, 1141-1148 (2012)

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