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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 6 — Jun. 1, 2012
  • pp: 1350–1364

Microfluidics based phantoms of superficial vascular network

Long Luu, Patrick A. Roman, Scott A. Mathews, and Jessica C. Ramella-Roman  »View Author Affiliations


Biomedical Optics Express, Vol. 3, Issue 6, pp. 1350-1364 (2012)
http://dx.doi.org/10.1364/BOE.3.001350


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Abstract

Several new bio-photonic techniques aim to measure flow in the human vasculature non-destructively. Some of these tools, such as laser speckle imaging or Doppler optical coherence tomography, are now reaching the clinical stage. Therefore appropriate calibration and validation techniques dedicated to these particular measurements are therefore of paramount importance. In this paper we introduce a fast prototyping technique based on laser micromachining for the fabrication of dynamic flow phantoms. Micro-channels smaller than 20 µm in width can be formed in a variety of materials such as epoxies, plastics, and household tape. Vasculature geometries can be easily and quickly modified to accommodate a particular experimental scenario.

© 2012 OSA

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Calibration, Validation and Phantom Studies

History
Original Manuscript: March 21, 2012
Revised Manuscript: April 25, 2012
Manuscript Accepted: April 25, 2012
Published: May 14, 2012

Virtual Issues
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices (2012) Biomedical Optics Express
July 3, 2012 Spotlight on Optics

Citation
Long Luu, Patrick A. Roman, Scott A. Mathews, and Jessica C. Ramella-Roman, "Microfluidics based phantoms of superficial vascular network," Biomed. Opt. Express 3, 1350-1364 (2012)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-3-6-1350


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