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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 7 — Jul. 1, 2012
  • pp: 1557–1564

Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit

Kenneth K. C. Lee, Adrian Mariampillai, Joe X. Z. Yu, David W. Cadotte, Brian C. Wilson, Beau A. Standish, and Victor X. D. Yang  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 7, pp. 1557-1564 (2012)

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Abstract: Advances in swept source laser technology continues to increase the imaging speed of swept-source optical coherence tomography (SS-OCT) systems. These fast imaging speeds are ideal for microvascular detection schemes, such as speckle variance (SV), where interframe motion can cause severe imaging artifacts and loss of vascular contrast. However, full utilization of the laser scan speed has been hindered by the computationally intensive signal processing required by SS-OCT and SV calculations. Using a commercial graphics processing unit that has been optimized for parallel data processing, we report a complete high-speed SS-OCT platform capable of real-time data acquisition, processing, display, and saving at 108,000 lines per second. Subpixel image registration of structural images was performed in real-time prior to SV calculations in order to reduce decorrelation from stationary structures induced by the bulk tissue motion. The viability of the system was successfully demonstrated in a high bulk tissue motion scenario of human fingernail root imaging where SV images (512 × 512 pixels, n = 4) were displayed at 54 frames per second.

© 2012 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Optical Coherence Tomography

Original Manuscript: April 25, 2012
Revised Manuscript: May 30, 2012
Manuscript Accepted: June 5, 2012
Published: June 7, 2012

Kenneth K. C. Lee, Adrian Mariampillai, Joe X. Z. Yu, David W. Cadotte, Brian C. Wilson, Beau A. Standish, and Victor X. D. Yang, "Real-time speckle variance swept-source optical coherence tomography using a graphics processing unit," Biomed. Opt. Express 3, 1557-1564 (2012)

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