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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 8 — Aug. 1, 2012
  • pp: 1880–1890

Dual-mode laparoscopic fluorescence image-guided surgery using a single camera

Daniel C. Gray, Evgenia M. Kim, Victoria E. Cotero, Anshika Bajaj, V. Paul Staudinger, Cristina A. Tan Hehir, and Siavash Yazdanfar  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 8, pp. 1880-1890 (2012)

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Iatrogenic nerve damage is a leading cause of morbidity associated with many common surgical procedures. Complications arising from these injuries may result in loss of function and/or sensation, muscle atrophy, and chronic neuropathy. Fluorescence image-guided surgery offers a potential solution for avoiding intraoperative nerve damage by highlighting nerves that are otherwise difficult to visualize. In this work we present the development of a single camera, dual-mode laparoscope that provides near simultaneous display of white-light and fluorescence images of nerves. The capability of the instrumentation is demonstrated through imaging several types of in situ rat nerves via a nerve specific contrast agent. Full color white light and high brightness fluorescence images and video of nerves as small as 100 µm in diameter are presented.

© 2012 OSA

OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(300.2530) Spectroscopy : Fluorescence, laser-induced

ToC Category:
Endoscopes, Catheters and Micro-Optics

Original Manuscript: May 15, 2012
Revised Manuscript: June 26, 2012
Manuscript Accepted: July 1, 2012
Published: July 17, 2012

Daniel C. Gray, Evgenia M. Kim, Victoria E. Cotero, Anshika Bajaj, V. Paul Staudinger, Cristina A. Tan Hehir, and Siavash Yazdanfar, "Dual-mode laparoscopic fluorescence image-guided surgery using a single camera," Biomed. Opt. Express 3, 1880-1890 (2012)

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