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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 9 — Sep. 1, 2012
  • pp: 2100–2110

Ultrasound modulation of coherent light in a multiple-scattering medium: experimental verification of nonzero average phase carried by light

Mayanglambam Suheshkumar Singh, Rajan Kanhirodan, Ram Mohan Vasu, and Debasish Roy  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 9, pp. 2100-2110 (2012)

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We demonstrate the phase fluctuation introduced by oscillation of scattering centers in the focal volume of an ultrasound transducer in an optical tomography experiment has a nonzero mean. The conditions to be met for the above are: (i) the frequency of the ultrasound should be in the vicinity of the most dominant natural frequency of vibration of the ultrasound focal volume, (ii) the corresponding acoustic wavelength should be much larger than n *, a modified transport mean-free-path applicable for phase decorrelation and (iii) the focal volume of the ultrasound transducer should not be larger than 4 – 5 times ( n * ) 3. We demonstrate through simulations that as the ratio of the ultrasound focal volume to ( n * ) 3 increases, the average of the phase fluctuation decreases and becomes zero when the focal volume becomes greater than around 4 ( n * ) 3; and through simulations and experiments that as the acoustic frequency increases from 100 Hz to 1 MHz, the average phase decreases to zero. Through experiments done in chicken breast we show that the average phase increases from around 110° to 130° when the background medium is changed from water to glycerol, indicating that the average of the phase fluctuation can be used to sense changes in refractive index deep within tissue.

© 2012 OSA

OCIS Codes
(110.0110) Imaging systems : Imaging systems
(110.6150) Imaging systems : Speckle imaging
(110.7170) Imaging systems : Ultrasound
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Multimodal Imaging

Original Manuscript: June 6, 2012
Manuscript Accepted: July 4, 2012
Published: August 13, 2012

Mayanglambam Suheshkumar Singh, Rajan Kanhirodan, Ram Mohan Vasu, and Debasish Roy, "Ultrasound modulation of coherent light in a multiple-scattering medium: experimental verification of nonzero average phase carried by light," Biomed. Opt. Express 3, 2100-2110 (2012)

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