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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 10 — Oct. 1, 2013
  • pp: 1909–1924

Blood flow velocity quantification using split-spectrum amplitude-decorrelation angiography with optical coherence tomography

Jason Tokayer, Yali Jia, Al-Hafeez Dhalla, and David Huang  »View Author Affiliations


Biomedical Optics Express, Vol. 4, Issue 10, pp. 1909-1924 (2013)
http://dx.doi.org/10.1364/BOE.4.001909


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Abstract

The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was recently developed as a method for imaging blood flow in the human retina without the use of phase information. In order to enable absolute blood velocity quantification, in vitro phantom experiments are performed to correlate the SSADA signal at multiple time scales with various preset velocities. A linear model relating SSADA measurements to absolute flow velocities is derived using the phantom data. The operating range for the linear model is discussed along with its implication for velocity quantification with SSADA in a clinical setting.

© 2013 OSA

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Optical Coherence Tomography

History
Original Manuscript: July 17, 2013
Revised Manuscript: August 22, 2013
Manuscript Accepted: August 27, 2013
Published: September 3, 2013

Citation
Jason Tokayer, Yali Jia, Al-Hafeez Dhalla, and David Huang, "Blood flow velocity quantification using split-spectrum amplitude-decorrelation angiography with optical coherence tomography," Biomed. Opt. Express 4, 1909-1924 (2013)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-4-10-1909


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