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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 10 — Oct. 1, 2013
  • pp: 2196–2206

Achromatic miniature lens system for coherent Raman scattering microscopy

Richa Mittal, Mihaela Balu, Petra Wilder-Smith, and Eric O. Potma  »View Author Affiliations


Biomedical Optics Express, Vol. 4, Issue 10, pp. 2196-2206 (2013)
http://dx.doi.org/10.1364/BOE.4.002196


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Abstract

We discuss the design and performance of a miniature objective lens optimized for coherent Raman scattering microscopy. The packaged lens assembly has a numerical aperture of 0.51 in water and an outer diameter of 8 mm. The lens system exhibits minimum chromatic aberrations, and produces coherent Raman scattering images with sub-micrometer lateral resolution (0.648 μm) using near-infrared excitation pulses. We demonstrate that despite the small dimensions of the miniature objective, the performance of this lens system is comparable to standard microscope objective lenses, offering opportunities for miniaturizing coherent Raman scattering imaging probes without sacrificing the image quality.

© 2013 OSA

OCIS Codes
(220.3630) Optical design and fabrication : Lenses
(350.3950) Other areas of optics : Micro-optics
(180.4315) Microscopy : Nonlinear microscopy

ToC Category:
Microscopy

History
Original Manuscript: June 17, 2013
Revised Manuscript: August 3, 2013
Manuscript Accepted: August 23, 2013
Published: September 19, 2013

Virtual Issues
Optical Molecular Probes, Imaging, and Drug Delivery (2013) Biomedical Optics Express

Citation
Richa Mittal, Mihaela Balu, Petra Wilder-Smith, and Eric O. Potma, "Achromatic miniature lens system for coherent Raman scattering microscopy," Biomed. Opt. Express 4, 2196-2206 (2013)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-4-10-2196


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