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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 10 — Oct. 1, 2013
  • pp: 2224–2230

A least-squares fixed-point iterative algorithm for multiple illumination photoacoustic tomography

Tyler Harrison, Peng Shao, and Roger J. Zemp  »View Author Affiliations

Biomedical Optics Express, Vol. 4, Issue 10, pp. 2224-2230 (2013)

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The optical absorption of tissues provides important information for clinical and pre-clinical studies. The challenge in recovering optical absorption from photoacoustic images is that the measured pressure depends on absorption and local fluence. One reconstruction approach uses a fixed-point iterative technique based on minimizing the mean-squared error combined with modeling of the light source to determine optical absorption. With this technique, convergence is not guaranteed even with an accurate measure of optical scattering. In this work we demonstrate using simulations that a new multiple illumination least squares fixed-point iteration algorithm improves convergence - even with poor estimates of optical scattering.

© 2013 OSA

OCIS Codes
(100.0100) Image processing : Image processing
(100.3010) Image processing : Image reconstruction techniques
(110.5120) Imaging systems : Photoacoustic imaging
(110.6960) Imaging systems : Tomography

ToC Category:
Image Reconstruction and Inverse Problems

Original Manuscript: July 3, 2013
Revised Manuscript: September 5, 2013
Manuscript Accepted: September 11, 2013
Published: September 24, 2013

Tyler Harrison, Peng Shao, and Roger J. Zemp, "A least-squares fixed-point iterative algorithm for multiple illumination photoacoustic tomography," Biomed. Opt. Express 4, 2224-2230 (2013)

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