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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 11 — Nov. 1, 2013
  • pp: 2450–2462

Computational analysis of endometrial photocoagulation with diffusing optical device

Jinhee Kwon, Chang-Yong Lee, Junghwan Oh, and Hyun Wook Kang  »View Author Affiliations

Biomedical Optics Express, Vol. 4, Issue 11, pp. 2450-2462 (2013)

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A balloon-catheter optical diffuser for endometrial treatment was evaluated with computational thermal analysis. Various catheter materials and dimensions were implemented to identify the optimal design for the device. Spatial and temporal development of temperature during 30-sec irradiation of 532-nm light demonstrated thermal insulation effects of polyurethane on temperature increase up to 384 K, facilitating the irreversible denaturation. The current model revealed the degree of thermal coagulation 13% thicker than experimental results possibly due to lack of tissue dynamics and light intensity distribution. In combination with photon distribution, the analytical simulation can be a feasible tool to optimize the new optical diffuser for efficient and safe endometrial treatment.

© 2013 Optical Society of America

OCIS Codes
(000.4430) General : Numerical approximation and analysis
(120.6810) Instrumentation, measurement, and metrology : Thermal effects
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4440) Medical optics and biotechnology : ObGyn

ToC Category:
Optical Therapies and Photomodificaton

Original Manuscript: July 30, 2013
Revised Manuscript: October 8, 2013
Manuscript Accepted: October 8, 2013
Published: October 14, 2013

Virtual Issues
Advances in Optics for Biotechnology, Medicine and Surgery (2013) Biomedical Optics Express

Jinhee Kwon, Chang-Yong Lee, Junghwan Oh, and Hyun Wook Kang, "Computational analysis of endometrial photocoagulation with diffusing optical device," Biomed. Opt. Express 4, 2450-2462 (2013)

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