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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 3 — Mar. 1, 2013
  • pp: 427–432

Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror

Hao Yang, Lei Xi, Sean Samuelson, Huikai Xie, Lily Yang, and Huabei Jiang  »View Author Affiliations

Biomedical Optics Express, Vol. 4, Issue 3, pp. 427-432 (2013)

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We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.

© 2013 OSA

OCIS Codes
(110.6960) Imaging systems : Tomography
(170.0110) Medical optics and biotechnology : Imaging systems
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Multimodal Imaging

Original Manuscript: December 7, 2012
Revised Manuscript: January 19, 2013
Manuscript Accepted: February 13, 2013
Published: February 15, 2013

Hao Yang, Lei Xi, Sean Samuelson, Huikai Xie, Lily Yang, and Huabei Jiang, "Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror," Biomed. Opt. Express 4, 427-432 (2013)

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