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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 4 — Apr. 1, 2013
  • pp: 500–513

A coherent model for turbid imaging with confocal microscopy

Christopher E. Glazowski and James Zavislan  »View Author Affiliations


Biomedical Optics Express, Vol. 4, Issue 4, pp. 500-513 (2013)
http://dx.doi.org/10.1364/BOE.4.000500


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Abstract

We present an engineering model of coherent imaging within a turbid volume, such as human tissues, with a confocal microscope. The model is built to analyze the statistical effect of aberrations and multiply scattered light on the resulting image. Numerical modeling of theory is compared with experimental results. We describe the construction of a stable phantom that represents the statistical effect of object turbidity on the image recorded. The model and phantom can serve as basis for system optimization in turbid imaging.

© 2013 OSA

OCIS Codes
(170.1790) Medical optics and biotechnology : Confocal microscopy
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(110.0113) Imaging systems : Imaging through turbid media

ToC Category:
Optics of Tissue and Turbid Media

History
Original Manuscript: December 12, 2012
Revised Manuscript: February 19, 2013
Manuscript Accepted: February 22, 2013
Published: March 4, 2013

Citation
Christopher E. Glazowski and James Zavislan, "A coherent model for turbid imaging with confocal microscopy," Biomed. Opt. Express 4, 500-513 (2013)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-4-4-500


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