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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 8 — Aug. 1, 2013
  • pp: 1380–1389

Simultaneous three-dimensional photoacoustic and laser-ultrasound tomography

Gerhild Wurzinger, Robert Nuster, Nicole Schmitner, Sibylle Gratt, Dirk Meyer, and Günther Paltauf  »View Author Affiliations


Biomedical Optics Express, Vol. 4, Issue 8, pp. 1380-1389 (2013)
http://dx.doi.org/10.1364/BOE.4.001380


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Abstract

A tomographic setup that provides the co-registration of photoacoustic (PA) and ultrasound (US) images is presented. For pulse-echo US-tomography laser-induced broadband plane ultrasonic waves are produced by illuminating an optically absorbing target with a short near-infrared laser pulse. Part of the same pulse is frequency doubled and used for the generation of PA waves within the object of interest. The laser-generated plane waves are scattered at the imaging object and measured with the same interferometric detector that also acquires the photoacoustic signals. After collection and separation of the data image reconstruction is done using back-projection resulting in three-dimensional, co-registered PA and US images. The setup is characterized and the resolution in PA and US mode is estimated to be about 85 µm and 40 µm, respectively. Besides measurements on phantoms the performance is also tested on a biological sample.

© 2013 Optical Society of America

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(110.7170) Imaging systems : Ultrasound

ToC Category:
Photoacoustic Imaging and Spectroscopy

History
Original Manuscript: April 16, 2013
Revised Manuscript: June 27, 2013
Manuscript Accepted: July 17, 2013
Published: July 19, 2013

Citation
Gerhild Wurzinger, Robert Nuster, Nicole Schmitner, Sibylle Gratt, Dirk Meyer, and Günther Paltauf, "Simultaneous three-dimensional photoacoustic and laser-ultrasound tomography," Biomed. Opt. Express 4, 1380-1389 (2013)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-4-8-1380


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