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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 9 — Sep. 1, 2013
  • pp: 1494–1503

Dual modality endomicroscope with optical zoom capability

Dimitre G. Ouzounov, David R. Rivera, Wendy O. Williams, John A. Stupinski, Teresa L. Southard, Kelly H. Hume, Julie Bentley, Robert S. Weiss, Watt W. Webb, and Chris Xu  »View Author Affiliations


Biomedical Optics Express, Vol. 4, Issue 9, pp. 1494-1503 (2013)
http://dx.doi.org/10.1364/BOE.4.001494


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Abstract

We present a miniature endomicroscope that combines large field-of-view (FOV) (1.15 mm) reflectance imaging with high-resolution (~0.5 μm) multiphoton intrinsic fluorescence imaging. We acquired in vivo and ex vivo images of unstained normal and tumor-laden tissues by using the large-FOV mode to navigate to the site of interest and then switching to the high-resolution modality to resolve cellular details.

© 2013 OSA

OCIS Codes
(110.2350) Imaging systems : Fiber optics imaging
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(180.4315) Microscopy : Nonlinear microscopy

ToC Category:
Endoscopes, Catheters and Micro-Optics

History
Original Manuscript: June 28, 2013
Manuscript Accepted: July 21, 2013
Published: August 1, 2013

Virtual Issues
Bio-Optics: Design and Applications (2013) Biomedical Optics Express

Citation
Dimitre G. Ouzounov, David R. Rivera, Wendy O. Williams, John A. Stupinski, Teresa L. Southard, Kelly H. Hume, Julie Bentley, Robert S. Weiss, Watt W. Webb, and Chris Xu, "Dual modality endomicroscope with optical zoom capability," Biomed. Opt. Express 4, 1494-1503 (2013)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-4-9-1494


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