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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 9 — Sep. 1, 2013
  • pp: 1662–1672

Calibration of a prototype NIRS oximeter against two commercial devices on a blood-lipid phantom

Simon Hyttel-Sorensen, Stefan Kleiser, Martin Wolf, and Gorm Greisen  »View Author Affiliations

Biomedical Optics Express, Vol. 4, Issue 9, pp. 1662-1672 (2013)

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In a blood-lipid liquid phantom the prototype near-infrared spectroscopy oximeter OxyPrem was calibrated against the INVOS® 5100c adult sensor in respect to values of regional tissue oxygen haemoglobin saturation (rStO2) for possible inclusion in the randomised clinical trial - SafeBoosC. In addition different commercial NIRS oximeters were compared on changing haemoglobin oxygen saturation and compared against co-oximetry. The best calibration was achieved with a simple offset and a linear scaling of the OxyPrem rStO2 values. The INVOS adult and pediatric sensor gave systematically different values, while the difference between the NIRO® 300 and the two INVOS sensors were magnitude dependent. The co-oximetry proved unreliable on such low haemoglobin and high Intralipid levels.

© 2013 OSA

OCIS Codes
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(300.6190) Spectroscopy : Spectrometers

ToC Category:
Calibration, Validation and Phantom Studies

Original Manuscript: May 16, 2013
Revised Manuscript: June 27, 2013
Manuscript Accepted: June 28, 2013
Published: August 14, 2013

Simon Hyttel-Sorensen, Stefan Kleiser, Martin Wolf, and Gorm Greisen, "Calibration of a prototype NIRS oximeter against two commercial devices on a blood-lipid phantom," Biomed. Opt. Express 4, 1662-1672 (2013)

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