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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 3 — Mar. 1, 2014
  • pp: 788–799

Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography

Kushal Wijesundara, Carlton Zdanski, Julia Kimbell, Hillel Price, Nicusor Iftimia, and Amy L. Oldenburg  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 3, pp. 788-799 (2014)
http://dx.doi.org/10.1364/BOE.5.000788


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Abstract

Minimally invasive imaging of upper airway obstructions in children and adults is needed to improve clinical decision-making. Toward this goal, we demonstrate an anatomical optical coherence tomography (aOCT) system delivered via a small-bore, flexible endoscope to quantify the upper airway lumen geometry. Helical scans were obtained from a proximally-scanned fiber-optic catheter of 820 μm outer diameter and >2 mm focal length. Coupled with a long coherence length wavelength-swept light source, the system exhibited an SNR roll-off of < 10 dB over a 10 mm range. Operating at 10 rotations/s, the average accuracy of segmented cross-sectional areas was found to be −1.4 ± 1.0%. To demonstrate the capability of this system, aOCT was performed on a pediatric airway phantom and on ex vivo swine trachea. The ability for quantitative endoscopy afforded by this system can aid in diagnosis, medical and surgical decision making, and predictive modeling of upper airway obstructive disorders.

© 2014 Optical Society of America

OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Endoscopes, Catheters and Micro-Optics

History
Original Manuscript: December 24, 2013
Revised Manuscript: February 3, 2014
Manuscript Accepted: February 3, 2014
Published: February 19, 2014

Citation
Kushal Wijesundara, Carlton Zdanski, Julia Kimbell, Hillel Price, Nicusor Iftimia, and Amy L. Oldenburg, "Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography," Biomed. Opt. Express 5, 788-799 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-3-788


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