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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 3 — Mar. 1, 2014
  • pp: 882–894

2-D PSTD Simulation of the time-reversed ultrasound-encoded deep-tissue imaging technique

Snow H. Tseng, Wei-Lun Ting, and Shiang-Jiu Wang  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 3, pp. 882-894 (2014)
http://dx.doi.org/10.1364/BOE.5.000882


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Abstract

We present a robust simulation technique to model the time-reversed ultrasonically encoded (TRUE) technique for deep-tissue imaging. The pseudospectral time-domain (PSTD) algorithm is employed to rigorously model the electromagnetic wave interaction of light propagating through a macroscopic scattering medium. Based upon numerical solutions of Maxwell’s equations, the amplitude and phase are accurately accounted for to analyze factors that affect the TRUE propagation of light through scattering media. More generally, we demonstrate the feasibility of modeling light propagation through a virtual tissue model of macroscopic dimensions with numerical solutions of Maxwell’s equations.

© 2014 Optical Society of America

OCIS Codes
(290.4210) Scattering : Multiple scattering
(290.7050) Scattering : Turbid media

ToC Category:
Optics of Tissue and Turbid Media

History
Original Manuscript: February 11, 2014
Manuscript Accepted: February 20, 2014
Published: February 25, 2014

Citation
Snow H. Tseng, Wei-Lun Ting, and Shiang-Jiu Wang, "2-D PSTD Simulation of the time-reversed ultrasound-encoded deep-tissue imaging technique," Biomed. Opt. Express 5, 882-894 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-3-882


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References

  1. Y. M. Wang, B. Judkewitz, C. A. DiMarzio, and C. H. Yang, “Deep-tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light,” Nat. Commun.3, 928 (2012).
  2. X. Xu, H. Liu, and L. V. Wang, “Time-reversed ultrasonically encoded optical focusing into scattering media,” Nat. Photonics5(3), 154–157 (2011). [CrossRef] [PubMed]
  3. K. Si, R. Fiolka, and M. Cui, “Fluorescence imaging beyond the ballistic regime by ultrasound pulse guided digital phase conjugation,” Nat. Photonics6(10), 657–661 (2012). [CrossRef] [PubMed]
  4. J. L. Hollmann, R. Horstmeyer, C. Yang, and C. A. DiMarzio, “Analysis and modeling of an ultrasound-modulated guide star to increase the depth of focusing in a turbid medium,” J. Biomed. Opt.18(2), 025004 (2013). [CrossRef] [PubMed]
  5. S. H. Tseng, “PSTD Simulation of optical phase conjugation of light propagating long optical paths,” Opt. Express17(7), 5490–5495 (2009). [CrossRef] [PubMed]
  6. S. H. Tseng, “Investigating the Optical Phase Conjugation Reconstruction Phenomenon of Light Multiply Scattered by a Random Medium,” IEEE Photon. J.2(4), 636–641 (2010). [CrossRef]
  7. Q. H. Liu, “Large-scale simulations of electromagnetic and acoustic measurements using the pseudospectral time-domain (PSTD) algorithm,” IEEE Trans. Geosci. Rem. Sens.37(2), 917–926 (1999). [CrossRef]
  8. S. D. Gedney, “An anisotropic perfectly matched layer-absorbing medium for the truncation of FDTD lattices,” IEEE Trans. Antenn. Propag.44(12), 1630–1639 (1996). [CrossRef]
  9. Y. Huang, C. Tsai, W. Ting, and S. H. Tseng, “PSTD simulation of the continuous-wave optical phase conjugation phenomenon,” In Review.
  10. A. Taflove and S. C. Hagness, Computational Electrodynamics: the finite-difference time-domain method (Artech House, 2000).
  11. W. Choi, C. Fang-Yen, K. Badizadegan, S. Oh, N. Lue, R. R. Dasari, and M. S. Feld, “Tomographic phase microscopy,” Nat. Methods4(9), 717–719 (2007). [CrossRef] [PubMed]

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