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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 3 — Mar. 1, 2014
  • pp: 975–989

Reliable recovery of the optical properties of multi-layer turbid media by iteratively using a layered diffusion model at multiple source-detector separations

Yu-Kai Liao and Sheng-Hao Tseng  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 3, pp. 975-989 (2014)
http://dx.doi.org/10.1364/BOE.5.000975


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Abstract

Accurately determining the optical properties of multi-layer turbid media using a layered diffusion model is often a difficult task and could be an ill-posed problem. In this study, an iterative algorithm was proposed for solving such problems. This algorithm employed a layered diffusion model to calculate the optical properties of a layered sample at several source-detector separations (SDSs). The optical properties determined at various SDSs were mutually referenced to complete one round of iteration and the optical properties were gradually revised in further iterations until a set of stable optical properties was obtained. We evaluated the performance of the proposed method using frequency domain Monte Carlo simulations and found that the method could robustly recover the layered sample properties with various layer thickness and optical property settings. It is expected that this algorithm can work with photon transport models in frequency and time domain for various applications, such as determination of subcutaneous fat or muscle optical properties and monitoring the hemodynamics of muscle.

© 2014 Optical Society of America

OCIS Codes
(170.5270) Medical optics and biotechnology : Photon density waves
(170.5280) Medical optics and biotechnology : Photon migration
(290.1990) Scattering : Diffusion

ToC Category:
Optics of Tissue and Turbid Media

History
Original Manuscript: January 1, 2014
Revised Manuscript: February 9, 2014
Manuscript Accepted: February 21, 2014
Published: February 27, 2014

Citation
Yu-Kai Liao and Sheng-Hao Tseng, "Reliable recovery of the optical properties of multi-layer turbid media by iteratively using a layered diffusion model at multiple source-detector separations," Biomed. Opt. Express 5, 975-989 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-3-975


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