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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 4 — Apr. 1, 2014
  • pp: 1075–1089

Contact-free monitoring of circulation and perfusion dynamics based on the analysis of thermal imagery

Carina Barbosa Pereira, Michael Czaplik, Nikolai Blanik, Rolf Rossaint, Vladimir Blazek, and Steffen Leonhardt  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 4, pp. 1075-1089 (2014)
http://dx.doi.org/10.1364/BOE.5.001075


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Abstract

Acute circulatory disorders are commonly associated with systemic inflammatory response (SIRS) and sepsis. During sepsis, microcirculatory perfusion is compromised leading to tissue hypoperfusion and potentially to multiple organ dysfunction. In the present study, acute lung injury (ALI), one of the major causes leading to SIRS and sepsis, was experimentally induced in six female pigs. To investigate the progress of body temperature distribution, measurements with a long-wave infrared camera were carried out. Temperature centralization was evidenced during ALI owing to impairments of peripheral perfusion. In addition, statistical analysis demonstrated strong correlations between (a) standard deviation of the skin temperature distribution (SD) and shock index (SI) (p<0.0005), (b) SD and mean arterial pressure (MAP) (p<0.0005), (c) ΔT/Δx and SI (p<0.0005), as well as between (d) ΔT/Δx and MAP (p<0.0005). For clarification purposes, ΔT/Δx is a parameter implemented to quantify the spatial temperature gradient. This pioneering study created promising results. It demonstrated the capacity of infrared thermography as well as of the indexes, SD and ΔT/Δx, to detect impairments in both circulation and tissue perfusion.

© 2014 Optical Society of America

OCIS Codes
(040.3060) Detectors : Infrared
(170.1610) Medical optics and biotechnology : Clinical applications
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Cardiovascular Applications

History
Original Manuscript: November 20, 2013
Revised Manuscript: January 9, 2014
Manuscript Accepted: January 20, 2014
Published: March 5, 2014

Citation
Carina Barbosa Pereira, Michael Czaplik, Nikolai Blanik, Rolf Rossaint, Vladimir Blazek, and Steffen Leonhardt, "Contact-free monitoring of circulation and perfusion dynamics based on the analysis of thermal imagery," Biomed. Opt. Express 5, 1075-1089 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-4-1075


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