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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 5 — May. 1, 2014
  • pp: 1428–1444

Towards simultaneous Talbot bands based optical coherence tomography and scanning laser ophthalmoscopy imaging

Manuel J. Marques, Adrian Bradu, and Adrian Gh. Podoleanu  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 5, pp. 1428-1444 (2014)
http://dx.doi.org/10.1364/BOE.5.001428


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Abstract

We report a Talbot bands-based optical coherence tomography (OCT) system capable of producing longitudinal B-scan OCT images and en-face scanning laser ophthalmoscopy (SLO) images of the human retina in-vivo. The OCT channel employs a broadband optical source and a spectrometer. A gap is created between the sample and reference beams while on their way towards the spectrometer’s dispersive element to create Talbot bands. The spatial separation of the two beams facilitates collection by an SLO channel of optical power originating exclusively from the retina, deprived from any contribution from the reference beam. Three different modes of operation are presented, constrained by the minimum integration time of the camera used in the spectrometer and by the galvo-scanners’ scanning rate: (i) a simultaneous acquisition mode over the two channels, useful for small size imaging, that conserves the pixel-to-pixel correspondence between them; (ii) a hybrid sequential mode, where the system switches itself between the two regimes and (iii) a sequential “on-demand” mode, where the system can be used in either OCT or SLO regimes for as long as required. The two sequential modes present varying degrees of trade-off between pixel-to-pixel correspondence and independent full control of parameters within each channel. Images of the optic nerve and fovea regions obtained in the simultaneous (i) and in the hybrid sequential mode (ii) are presented.

© 2014 Optical Society of America

OCIS Codes
(110.0180) Imaging systems : Microscopy
(110.4190) Imaging systems : Multiple imaging
(110.4500) Imaging systems : Optical coherence tomography
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.1790) Medical optics and biotechnology : Confocal microscopy
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices

ToC Category:
Optical Coherence Tomography

History
Original Manuscript: February 26, 2014
Revised Manuscript: March 31, 2014
Manuscript Accepted: April 1, 2014
Published: April 4, 2014

Citation
Manuel J. Marques, Adrian Bradu, and Adrian Gh. Podoleanu, "Towards simultaneous Talbot bands based optical coherence tomography and scanning laser ophthalmoscopy imaging," Biomed. Opt. Express 5, 1428-1444 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-5-1428


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