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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 5 — May. 1, 2014
  • pp: 1445–1452

Measurement of cardiac output by use of noninvasively measured transient hemodilution curves with photoacoustic technology

Dongyel Kang, Qiaojian Huang, and Youzhi Li  »View Author Affiliations

Biomedical Optics Express, Vol. 5, Issue 5, pp. 1445-1452 (2014)

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We present the theoretical basis and experimental verification for cardiac output measurements using noninvasively measured hemodilution curves afforded with an indicator dilution technique and the emerging photoacoustic technology. A photoacoustic system noninvasively tracks a transient hemodilution effect induced by a bolus of isotonic saline as an indicator. As a result, a photoacoustic indicator dilution curve is obtained, which allows to estimate cardiac output from the developed algorithm. The experiments with a porcine blood circulatory phantom system demonstrated the feasibility of this technology towards the development of a noninvasive cardiac output measurement system for patient monitoring.

© 2014 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Cardiovascular Applications

Original Manuscript: December 24, 2013
Revised Manuscript: February 13, 2014
Manuscript Accepted: February 28, 2014
Published: April 7, 2014

Dongyel Kang, Qiaojian Huang, and Youzhi Li, "Measurement of cardiac output by use of noninvasively measured transient hemodilution curves with photoacoustic technology," Biomed. Opt. Express 5, 1445-1452 (2014)

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