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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 6 — Jun. 1, 2014
  • pp: 1757–1767

Spectral multiplexing and coherent-state decomposition in Fourier ptychographic imaging

Siyuan Dong, Radhika Shiradkar, Pariksheet Nanda, and Guoan Zheng  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 6, pp. 1757-1767 (2014)
http://dx.doi.org/10.1364/BOE.5.001757


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Abstract

Information multiplexing is important for biomedical imaging and chemical sensing. In this paper, we report a microscopy imaging technique, termed state-multiplexed Fourier ptychography (FP), for information multiplexing and coherent-state decomposition. Similar to a typical Fourier ptychographic setting, we use an array of light sources to illuminate the sample from different incident angles and acquire corresponding low-resolution images using a monochromatic camera. In the reported technique, however, multiple light sources are lit up simultaneously for information multiplexing, and the acquired images thus represent incoherent summations of the sample transmission profiles corresponding to different coherent states. We show that, by using the state-multiplexed FP recovery routine, we can decompose the incoherent mixture of the FP acquisitions to recover a high-resolution sample image. We also show that, color-multiplexed imaging can be performed by simultaneously turning on R/G/B LEDs for data acquisition. The reported technique may provide a solution for handling the partially coherent effect of light sources used in Fourier ptychographic imaging platforms. It can also be used to replace spectral filter, gratings or other optical components for spectral multiplexing and demultiplexing. With the availability of cost-effective broadband LEDs, the reported technique may open up exciting opportunities for computational multispectral imaging.

© 2014 Optical Society of America

OCIS Codes
(100.3190) Image processing : Inverse problems
(170.0180) Medical optics and biotechnology : Microscopy
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(110.4234) Imaging systems : Multispectral and hyperspectral imaging

ToC Category:
Microscopy

History
Original Manuscript: March 19, 2014
Revised Manuscript: May 4, 2014
Manuscript Accepted: May 5, 2014
Published: May 9, 2014

Citation
Siyuan Dong, Radhika Shiradkar, Pariksheet Nanda, and Guoan Zheng, "Spectral multiplexing and coherent-state decomposition in Fourier ptychographic imaging," Biomed. Opt. Express 5, 1757-1767 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-6-1757


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