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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 7 — Jul. 1, 2014
  • pp: 2333–2340

Noninvasive in-vehicle alcohol detection with wavelength-modulated differential photothermal radiometry

Xinxin Guo, Andreas Mandelis, Yijun Liu, Bo Chen, Qun Zhou, and Felix Comeau  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 7, pp. 2333-2340 (2014)
http://dx.doi.org/10.1364/BOE.5.002333


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Abstract

This study describes the potential of wavelength-modulated differential photothermal radiometry (WM-DPTR) for non-invasive in-vehicle alcohol detection which can be of great importance in reducing alcohol-impaired driving. Ethanol content in the range of concern, 0-100 blood alcohol concentration (BAC) in water phantoms and blood serum diffused in human skin in vitro were measured with high sensitivity. The results show that the WM-DPTR system can be optimized for alcohol detection with the combination of two sensitivity-tuning parameters, amplitude ratio R and phase shift ΔP. WM-DPTR has demonstrated the potential to be developed into a portable alcohol ignition interlock biosensor that could be fitted as a universal accessory in vehicles.

© 2014 Optical Society of America

OCIS Codes
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(300.6430) Spectroscopy : Spectroscopy, photothermal
(280.1415) Remote sensing and sensors : Biological sensing and sensors

ToC Category:
Biosensors and Molecular Diagnostics

History
Original Manuscript: May 1, 2014
Revised Manuscript: June 14, 2014
Manuscript Accepted: June 14, 2014
Published: June 18, 2014

Citation
Xinxin Guo, Andreas Mandelis, Yijun Liu, Bo Chen, Qun Zhou, and Felix Comeau, "Noninvasive in-vehicle alcohol detection with wavelength-modulated differential photothermal radiometry," Biomed. Opt. Express 5, 2333-2340 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-7-2333


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References

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