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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 8 — Aug. 1, 2014
  • pp: 2715–2725

Bone tissue phantoms for optical flowmeters at large interoptode spacing generated by 3D-stereolithography

Tiziano Binzoni, Alessandro Torricelli, Remo Giust, Bruno Sanguinetti, Paul Bernhard, and Lorenzo Spinelli  »View Author Affiliations

Biomedical Optics Express, Vol. 5, Issue 8, pp. 2715-2725 (2014)

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A bone tissue phantom prototype allowing to test, in general, optical flowmeters at large interoptode spacings, such as laser-Doppler flowmetry or diffuse correlation spectroscopy, has been developed by 3D-stereolithography technique. It has been demonstrated that complex tissue vascular systems of any geometrical shape can be conceived. Absorption coefficient, reduced scattering coefficient and refractive index of the optical phantom have been measured to ensure that the optical parameters reasonably reproduce real human bone tissue in vivo. An experimental demonstration of a possible use of the optical phantom, utilizing a laser-Doppler flowmeter, is also presented.

© 2014 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(280.2490) Remote sensing and sensors : Flow diagnostics

ToC Category:
Calibration, Validation and Phantom Studies

Original Manuscript: May 12, 2014
Revised Manuscript: June 30, 2014
Manuscript Accepted: July 12, 2014
Published: July 21, 2014

Tiziano Binzoni, Alessandro Torricelli, Remo Giust, Bruno Sanguinetti, Paul Bernhard, and Lorenzo Spinelli, "Bone tissue phantoms for optical flowmeters at large interoptode spacing generated by 3D-stereolithography," Biomed. Opt. Express 5, 2715-2725 (2014)

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