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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 8 — Aug. 1, 2014
  • pp: 2785–2790

Thermally enhanced signal strength and SNR improvement of photoacoustic radar module

Wei Wang and Andreas Mandelis  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 8, pp. 2785-2790 (2014)
http://dx.doi.org/10.1364/BOE.5.002785


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Abstract

A thermally enhanced method for improving photoacoustic imaging depth and signal-to-noise (SNR) ratio is presented in this paper. Experimental results showed that the maximum imaging depth increased by 20% through raising the temperature of absorbing biotissues (ex-vivo beef muscle) uniformly from 37 to 43°C, and the SNR was increased by 8%. The parameters making up the Gruneisen constant were investigated experimentally and theoretically. The studies showed that the Gruneisen constant of biotissues increases with temperature, and the results were found to be consistent with the photoacousitc radar theory.

© 2014 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Photoacoustic Imaging and Spectroscopy

History
Original Manuscript: May 9, 2014
Revised Manuscript: June 30, 2014
Manuscript Accepted: July 7, 2014
Published: July 25, 2014

Citation
Wei Wang and Andreas Mandelis, "Thermally enhanced signal strength and SNR improvement of photoacoustic radar module," Biomed. Opt. Express 5, 2785-2790 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-8-2785


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References

  1. J. L. Kovar, M. A. Simpson, A. Schutz-Geschwender, and D. M. Olive, “A systematic approach to the development of fluorescent contrast agents for optical imaging of mouse cancer models,” Anal. Biochem.367(1), 1–12 (2007). [CrossRef] [PubMed]
  2. B. Lashkari and A. Mandelis, “Comparison between pulsed laser and frequency-domain photoacoustic modalities: signal-to-noise ratio, contrast, resolution, and maximum depth detectivity,” Rev. Sci. Instrum.82(9), 094903 (2011). [CrossRef] [PubMed]
  3. G. Ku and L. V. Wang, “Deeply penetrating photoacoustic tomography in biological tissues enhanced with an optical contrast agent,” Opt. Lett.30(5), 507–509 (2005). [CrossRef] [PubMed]
  4. R. Alwi, S. Telenkov, A. Mandelis, T. Leshuk, F. Gu, S. Oladepo, and K. Michaelian, “Silica-coated super paramagnetic iron oxide nanoparticles (SPION) as biocompatible contrast agent in biomedical photoacoustics,” Biomed. Opt. Express3(10), 2500–2509 (2012). [CrossRef] [PubMed]
  5. G. Kelly, “Body temperature variability (part 1): a review of the history of body temperature and its variability due to site selection, biological rhythms, fitness, and aging,” Altern. Med. Rev.11(4), 278–293 (2006). [PubMed]
  6. P. A. Mackowiak and G. Worden, “Carl Reinhold August Wunderlich and the evolution of clinical thermometry,” Clin. Infect. Dis.18(3), 458–467 (1994). [CrossRef] [PubMed]
  7. M. Sund-Levander, C. Forsberg, and L. K. Wahren, “Normal oral, rectal, tympanic and axillary body temperature in adult men and women: a systematic literature review,” Scand. J. Caring Sci.16(2), 122–128 (2002). [CrossRef] [PubMed]
  8. H. I. Robins, W. H. Dennis, A. J. Neville, L. M. Shecterle, P. A. Martin, J. Grossman, T. E. Davis, S. R. Neville, W. K. Gillis, and B. F. Rusy, “A nontoxic system for 41.8 degrees C whole-body hyperthermia: results of a Phase I study using a radiant heat device,” Cancer Res.45(8), 3937–3944 (1985). [PubMed]
  9. L. F. Fajardo, “Pathological effects of hyperthermia in normal tissues,” Cancer Res.44(10Suppl), 4826s–4835s (1984). [PubMed]
  10. J. van der Zee, “Heating the patient: a promising approach?” Ann. Oncol.13(8), 1173–1184 (2002). [CrossRef] [PubMed]
  11. P. Sminia, J. van der Zee, J. Wondergem, and J. Haveman, “Effect of hyperthermia on the central nervous system: a review,” Int. J. Hyperthermia10(1), 1–30 (1994). [CrossRef] [PubMed]
  12. H. Siekmann, “Recommended maximum temperatures for touchable surfaces,” Appl. Ergon.21(1), 69–73 (1990). [CrossRef] [PubMed]
  13. I. V. Larina, K. V. Larin, and R. O. Esenaliev, “Real-time optoacoustic monitoring of temperature in tissues,” J. Phys. D Appl. Phys.38(15), 2633–2639 (2005). [CrossRef]
  14. M. Pramanik and L. V. Wang, “Thermoacoustic and photoacoustic sensing of temperature,” J. Biomed. Opt.14(5), 054024 (2009). [CrossRef] [PubMed]
  15. W. Wang and A. Mandelis, “Thermally enhanced photoacoustic imaging of biotissues,” presented at ICPPP 17th, Suzhou, China, 20–24 Oct. (2013).
  16. Y. Fan, A. Mandelis, G. Spirou, and I. A. Vitkin, “Development of a laser photothermoacoustic frequency-swept system for subsurface imaging: theory and experiment,” J. Acoust. Soc. Am.116(6), 3523–3533 (2004). [CrossRef] [PubMed]
  17. V. E. Gusev and A. A. Karabutov, Laser Optoacoustics (AIP, 1993).
  18. S. A. Telenkov and A. Mandelis, “Fourier-domain biophotoacoustic subsurface depth selective amplitude and phase imaging of turbid phantoms and biological tissue,” J. Biomed. Opt.11(4), 044006 (2006). [CrossRef] [PubMed]
  19. E. O. Brigham, The Fast Fourier Transform and its Applications (Prentice-Hall, 1988).
  20. R. A. Lawrie and D. Ledward, Lawrie’s Meat Science (Woodhead, 2006).
  21. A. M. Pearson and R. B. Young, Muscle and Meat Biochemistry (Academic, 1989).
  22. B. A. Fricke and B. R. Becker, “Evaluation of thermophysical property models for foods,” HVAC and R. Research.7(4), 311–330 (2001). [CrossRef]
  23. Y. Choi and M. R. Okos, “Effects of temperature and composition on the thermal properties of foods,” in Food Engineering and Process Applications: Transport Phenomena, M. Le Maguer and P. Jelen, ed. (Elsevier, 1986).
  24. V. A. Dubinskaya, L. S. Eng, L. B. Rebrow, and V. A. Bykov, “Comparative study of the state of water in various human tissues,” Bull. Exp. Biol. Med.144(3), 294–297 (2007). [CrossRef] [PubMed]
  25. J. A. Dean, ed., Lange’s Handbook of Chemistry (McGraw-Hill, 1973).
  26. N. S. Osborne, H. F. Stimson, and D. C. Ginnings, “Measurements of heat capacity and heat of vaporization of water in the range 0° to 100°C,” J. Res. Nat. Bur. Stand. (U.S.)23(2), 197–260 (1939).
  27. S. Temkin, Elements of Acoustics (Wiley, 1981).
  28. H. J. van Staveren, C. J. M. Moes, J. van Marie, S. A. Prahl, and M. J. van Gemert, “Light scattering in Intralipid-10% in the wavelength range of 400-1100 nm,” Appl. Opt.30(31), 4507–4514 (1991). [CrossRef] [PubMed]

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