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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 8 — Aug. 1, 2014
  • pp: 2856–2869

The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures

Juan Aguirre, Jordi Morales-Dalmau, Lutz Funk, Francesc Jara, Pau Turon, and Turgut Durduran  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 8, pp. 2856-2869 (2014)
http://dx.doi.org/10.1364/BOE.5.002856


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Abstract

The ex vivo and in vivo imaging, and quantitative characterization of the degradation of surgical sutures (∼500 μm diameter) up to ∼1cm depth is demonstrated using a custom dark-field photo-acoustic microscope (PAM). A practical algorithm is developed to accurately measure the suture diameter during the degradation process. The results from tissue simulating phantoms and mice are compared to ex vivo measurements with an optical microscope demonstrating that PAM has a great deal of potential to characterize the degradation process of surgical sutures. The implications of this work for industrial applications are discussed.

© 2014 Optical Society of America

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology

ToC Category:
Photoacoustic Imaging and Spectroscopy

History
Original Manuscript: May 12, 2014
Revised Manuscript: July 19, 2014
Manuscript Accepted: July 23, 2014
Published: July 29, 2014

Citation
Juan Aguirre, Jordi Morales-Dalmau, Lutz Funk, Francesc Jara, Pau Turon, and Turgut Durduran, "The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures," Biomed. Opt. Express 5, 2856-2869 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-8-2856


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