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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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3D high-density localization microscopy using hybrid astigmatic/ biplane imaging and sparse image reconstruction
Localization microscopy achieves nanoscale spatial resolution by iterative localization of sparsely activated...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3935-3948 (2014)

Real-time measurement of alveolar size and population using phase contrast x-ray imaging
Herein a propagation-based phase contrast x-ray imaging technique for measuring particle size and number is...
Biomedical Optics Express, Vol. 5 Issue 11, pp.4024-4038 (2014)

Laser induced breakdown spectroscopy for bone and cartilage differentiation - ex vivo study as a prospect for a laser surgery feedback mechanism
Laser surgery enables for very accurate, fast and clean modeling of tissue. The specific and controlled...
Biomedical Optics Express, Vol. 5 Issue 11, pp.4013-4023 (2014)

Nanoparticle assisted photothermal deformation of individual neuronal organelles and cells
Stimulation of the localized surface plasmon of metallic nanoparticles has been shown to be an effective...
Biomedical Optics Express, Vol. 5 Issue 11, pp.4002-4012 (2014)

Imaging cytosolic translocation of Mycobacteria with two-photon fluorescence resonance energy transfer microscopy
Transition from latency to active tuberculosis requires Mycobacterium tuberculosis (Mtb) to penetrate the...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3990-4001 (2014)

High-contrast coherent terahertz imaging of porcine tissue via swept-frequency feedback interferometry
There is considerable interest in the interrogation of biological tissue at terahertz (THz) frequencies,...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3981-3989 (2014)

Generating and measuring photochemical changes inside the brain using optical fibers: exploring stroke
We report here on the development of a method for inducing a stroke in a specific location within a mouse...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3975-3980 (2014)

Considering sources and detectors distributions for quantitative photoacoustic tomography
Photoacoustic tomography (PAT) is a hybrid imaging modality that takes advantage of high optical contrast...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3960-3974 (2014)

Feasibility of ablative fractional laser-assisted drug delivery with optical coherence tomography
Fractional resurfacing creates hundreds of microscopic wounds in the skin without injuring surrounding...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3949-3959 (2014)

Volumetric (3D) compressive sensing spectral domain optical coherence tomography
In this work, we proposed a novel three-dimensional compressive sensing (CS) approach for spectral domain...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3921-3934 (2014)

Rapid calculation of diffuse reflectance from a multilayered model by combination of the white Monte Carlo and adding-doubling methods
To rapidly derive a result for diffuse reflectance from a multilayered model that is equivalent to that of a...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3901-3920 (2014)

Quantitative evaluation of atlas-based high-density diffuse optical tomography for imaging of the human visual cortex
Image recovery in diffuse optical tomography (DOT) of the human brain often relies on accurate models of...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3882-3900 (2014)

Detecting nanoparticles in tissue using an optical iterative technique
Determining the physical penetration depth of nanoparticles (NPs) into tissues is a challenge that many...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3871-3881 (2014)

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Published

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published
BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

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Spotlight on Optics

Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy

The field of clinical in vivo retinal imaging has recently entered into a new and exciting stage, thanks to the recent... [more]

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

Surgical guidance remains an important, yet underdeveloped, application area of optical imaging techniques. In... [more]

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Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

Biomedical Optics Express - Feature Overview
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Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
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Biomedical Optics Express - Introduction by Joseph Izatt