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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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Smartphone instrument for portable enzyme- linked immunosorbent assays
We demonstrate the utilization of a smartphone camera as a spectrometer that is capable of measuring Enzyme...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3792-3806 (2014)

Reflectance confocal endomicroscope with optical axial scanning for in vivo imaging of the oral mucosa
This paper presents the design and evaluation of a reflectance confocal laser endomicroscope using a...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3781-3791 (2014)

Effect of irradiation distance on image contrast in epi-optoacoustic imaging of human volunteers
In combined clinical optoacoustic (OA) and ultrasound (US) imaging, epi-mode irradiation and detection...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3765-3780 (2014)

Non-invasive transdermal two-dimensional mapping of cutaneous oxygenation with a rapid-drying liquid bandage
Oxygen plays an important role in wound healing, as it is essential to biological functions such as cell...
Biomedical Optics Express, Vol. 5 Issue 11, pp.3748-3764 (2014)

Fast one-dimensional wave-front propagation for x-ray differential phase-contrast imaging
Numerical wave-optical simulations of X-ray differential phase-contrast imaging using grating interferometry...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3739-3747 (2014)

Fluorescent correlation spectroscopy measurements with adaptive optics in the intercellular space of spheroids
In this study we demonstrate the use of adaptive optics to correct the biasing effects of optical aberrations...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3730-3738 (2014)

Automated identification of basal cell carcinoma by polarization-sensitive optical coherence tomography
We report an automated classifier to detect the presence of basal cell carcinoma in images of mouse skin...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3717-3729 (2014)

Longitudinal label-free tracking of cell death dynamics in living engineered human skin tissue with a multimodal microscope
We demonstrate real-time, longitudinal, label-free tracking of apoptotic and necrotic cells in living tissue...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3699-3716 (2014)

Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography
The optical characterization of malignant and benign breast lesions is presented. Time-resolved transmittance...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3684-3698 (2014)

A comparison between two NIRS oximeters (INVOS, OxyPrem) using measurement on the arm of adults and head of infants after caesarean section
Previously the NIRS oximeter OxyPrem was calibrated by comparison to the INVOS in a blood-lipid phantom. The...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3671-3683 (2014)

Performance evaluation of endoscopic Cerenkov luminescence imaging system: in vitro and pseudotumor studies
By integrating the clinically used endoscope with the emerging Cerenkov luminescence imaging (CLI)...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3660-3670 (2014)

Shape-parameterized diffuse optical tomography holds promise for sensitivity enhancement of fluorescence molecular tomography
A fundamental approach to enhancing the sensitivity of the fluorescence molecular tomography (FMT) is to...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3640-3659 (2014)

A linear gradient line source facilitates the use of diffusion models with high order approximation for efficient, accurate turbid sample optical properties recovery
In this paper, we demonstrate that a scanning MEMS mirror can be employed to create a linear gradient line...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3628-3639 (2014)

In Progress

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • In Progress

Published

Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published
BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

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Spotlight on Optics

Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy

The field of clinical in vivo retinal imaging has recently entered into a new and exciting stage, thanks to the recent... [more]

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

Surgical guidance remains an important, yet underdeveloped, application area of optical imaging techniques. In... [more]

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Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

Biomedical Optics Express - Feature Overview
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Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
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Biomedical Optics Express - Introduction by Joseph Izatt