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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues

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Depth selectivity for the assessment of microstructure by polarization studies
A polarimetric imaging system capable of continuously selecting imaging depth in a turbid media is...
Biomedical Optics Express, Vol. 4 Issue 6, pp.958-966 (2013)

Digital holographic microscopy of the myelin figure structural dynamics and the effect of thermal gradient
Myelin figures (MFs) are cylindrical multilamellar lipid tubes that can be found in various healthy and...
Biomedical Optics Express, Vol. 4 Issue 6, pp.950-957 (2013)

Multimodal snapshot spectral imaging for oral cancer diagnostics: a pilot study
Optical imaging and spectroscopy have emerged as effective tools for detecting malignant changes associated...
Biomedical Optics Express, Vol. 4 Issue 6, pp.938-949 (2013)

Automatic cone photoreceptor segmentation using graph theory and dynamic programming
Geometrical analysis of the photoreceptor mosaic can reveal subclinical ocular pathologies. In this paper, we...
Biomedical Optics Express, Vol. 4 Issue 6, pp.924-937 (2013)

Talbot-defocus multiscan tomography using the synchrotron X-ray microscope to study the lacuno-canalicular network in mouse bone
The three-dimensional network of lacunae and canaliculi that regulates metabolism in bone contains osteocytes...
Biomedical Optics Express, Vol. 4 Issue 6, pp.917-923 (2013)

Chiral imaging of collagen by second-harmonic generation circular dichroism
We provide evidence that the chirality of collagen can give rise to strong second-harmonic generation...
Biomedical Optics Express, Vol. 4 Issue 6, pp.909-916 (2013)

Characterization and treatment monitoring of inflammatory arthritis by photoacoustic imaging: a study on adjuvant-induced arthritis rat model
Neovascularity also known as angiogenesis is an early feature of inflammatory arthritis disease. Therefore,...
Biomedical Optics Express, Vol. 4 Issue 6, pp.900-908 (2013)

Simple buffers for 3D STORM microscopy
3D STORM is one of the leading methods for super-resolution imaging, with resolution down to 10 nm in the...
Biomedical Optics Express, Vol. 4 Issue 6, pp.885-899 (2013)

Time-averaged fluorescence intensity analysis in fluorescence fluctuation polarization sensitive experiments
In fluorescence fluctuation polarization sensitive experiments, the limitations associated with detecting the...
Biomedical Optics Express, Vol. 4 Issue 6, pp.868-884 (2013)

Lowered threshold energy for femtosecond laser induced optical breakdown in a water based eye model by aberration correction with adaptive optics
In femtosecond laser ophthalmic surgery tissue dissection is achieved by photodisruption based on laser...
Biomedical Optics Express, Vol. 4 Issue 6, pp.852-867 (2013)

Characterizing optical properties of nano contrast agents by using cross-referencing OCT imaging
We report a cross-referencing method to quickly and accurately characterize the optical properties of...
Biomedical Optics Express, Vol. 4 Issue 6, pp.842-851 (2013)

Simultaneous spatial and temporal focusing for tissue ablation
Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low...
Biomedical Optics Express, Vol. 4 Issue 6, pp.831-841 (2013)

Impact on stereo-acuity of two presbyopia correction approaches: monovision and small aperture inlay
Some of the different currently applied approaches that correct presbyopia may reduce stereovision. In this...
Biomedical Optics Express, Vol. 4 Issue 6, pp.822-830 (2013)

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Call for Papers

Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Submission Deadline: 15 June 2013
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Submission Deadline: 15 June 2013
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Submission Deadline: 15 June 2013
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Submission Deadline: 15 June 2013

Published

BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published
Cellular Imaging of the Retina
  • Joseph Carroll, Michael Pircher, Robert J. Zawadzki
  • Published
Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy
  • Xingde Li, Paul Beard, and Irene Georgakoudi
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

Video Discussion

Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes

Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes
Views: 155
Bilal Khan, Univ. Texas Arlington, discusses a brush optode to improve optical contact with the scalp for brain function imaging.

Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments

Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments
Views: 268
Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments

Images of Rod Photoreceptors Inside the Living Human Eye

Images of Rod Photoreceptors Inside the Living Human Eye
Views: 2173
Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

Biomedical Optics Express - Feature Overview
Views: 378
Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
Views: 576
Biomedical Optics Express - Introduction by Joseph Izatt

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Spotlight on Optics

Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT

In the latest paper from Robert Huber’s group, Thomas Klein presents the joined aperture OCT (JA-OCT) detection scheme,... [more]

A GAMOS plug-in for GEANT4 based Monte Carlo simulation of radiation-induced light transport in biological media

Cerenkov light emission from beta-emitting radionuclides was first measured in biological tissue less than five years... [more]

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