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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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Optically buffered Jones-matrix-based multifunctional optical coherence tomography with polarization mode dispersion correction
Polarization mode dispersion (PMD) degrades the performance of Jones-matrix-based polarization-sensitive...
Biomedical Optics Express, Vol. 6 Issue 1, pp.225-243 (2015)

MEMS scanning micromirror for optical coherence tomography
This paper describes an endoscopic-inspired imaging system employing a micro-electromechanical system (MEMS)...
Biomedical Optics Express, Vol. 6 Issue 1, pp.211-224 (2015)

Lensed fiber-optic probe design for efficient photon collection in scattering media
Abstract: Measurement of bioluminescent or fluorescent optical reporters with an implanted fiber-optic probe...
Biomedical Optics Express, Vol. 6 Issue 1, pp.191-210 (2015)

Two-dimensional micro-displacement measurement for laser coagulation using optical coherence tomography
To improve the reproducibility of photocoagulation, the ability to quantitatively monitor the thermal change...
Biomedical Optics Express, Vol. 6 Issue 1, pp.170-190 (2015)

Automatic segmentation of microcystic macular edema in OCT
Microcystic macular edema (MME) manifests as small, hyporeflective cystic areas within the retina. For...
Biomedical Optics Express, Vol. 6 Issue 1, pp.155-169 (2015)

Spatial mapping of proteoglycan content in articular cartilage using near-infrared (NIR) spectroscopy
Diagnosis of articular cartilage pathology in the early disease stages using current clinical diagnostic...
Biomedical Optics Express, Vol. 6 Issue 1, pp.144-154 (2015)

Detection of cervical cancer based on photoacoustic imaging—the in-vitro results
In current clinical practice, the diagnosis of cervical cancer (CC) is mainly through the cervical screening...
Biomedical Optics Express, Vol. 6 Issue 1, pp.135-143 (2015)

Visualization of fluid drainage pathways in lymphatic vessels and lymph nodes using a mouse model to test a lymphatic drug delivery system
Curing/preventing micrometastasis to lymph nodes (LNs) located outside the surgically resected area is...
Biomedical Optics Express, Vol. 6 Issue 1, pp.124-134 (2015)

Stretching of red blood cells using an electro-optics trap
The stretching stiffness of Red Blood Cells (RBCs) was investigated using a combination of an AC...
Biomedical Optics Express, Vol. 6 Issue 1, pp.118-123 (2015)

Evaluating the toxic effect of an antimicrobial agent on single bacterial cells with optical tweezers
We implement an optical tweezers technique to assess the effects of chemical agents on single bacterial...
Biomedical Optics Express, Vol. 6 Issue 1, pp.112-117 (2015)

Optimization of multimodal spectral imaging for assessment of resection margins during Mohs micrographic surgery for basal cell carcinoma
Multimodal spectral imaging (MSI) based on auto-fluorescence imaging and Raman micro-spectroscopy was used to...
Biomedical Optics Express, Vol. 6 Issue 1, pp.98-111 (2015)

Non-contact estimation of heart rate and oxygen saturation using ambient light
We propose a robust method for automated computation of heart rate (HR) from digital color video recordings...
Biomedical Optics Express, Vol. 6 Issue 1, pp.86-97 (2015)

Relation between speckle decorrelation and optical phase conjugation (OPC)-based turbidity suppression through dynamic scattering media: a study on in vivo mouse skin
Light scattering in biological tissue significantly limits the accessible depth for localized optical...
Biomedical Optics Express, Vol. 6 Issue 1, pp.72-85 (2015)

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Published

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published
BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

Spotlight on Optics

Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy

The field of clinical in vivo retinal imaging has recently entered into a new and exciting stage, thanks to the recent... [more]

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

Surgical guidance remains an important, yet underdeveloped, application area of optical imaging techniques. In... [more]

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Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

Biomedical Optics Express - Feature Overview
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Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
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Biomedical Optics Express - Introduction by Joseph Izatt