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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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Fibre-coupled multiphoton microscope with adaptive motion compensation
To address the challenge of sample motion during in vivo imaging, we present a fibre-coupled multiphoton...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1876-1884 (2015)

Rapid imaging of large tissues using high-resolution stage-scanning microscopy
Rapid and high-resolution imaging of large tissues is essential in biological research, like brain neuron...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1867-1875 (2015)

Deep, high contrast microscopic cell imaging using three-photon luminescence of β-(NaYF4:Er3+/NaYF4) nanoprobe excited by 1480-nm CW laser of only 1.5-mW
It is challenging to achieve deep microscopic imaging for the strong scattering in biotissue. An efficient...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1857-1866 (2015)

Decrease in fluorescence lifetime by glycation of collagen and its application in determining advanced glycation end-products in human dentin
Advanced Glycation End-products (AGEs) are produced by the Maillard reaction, which causes cross-linking of...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1844-1856 (2015)

Quantitative single-mode fiber based PS-OCT with single input polarization state using Mueller matrix
We present a simple but effective method to quantitatively measure the birefringence of tissue by an all...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1828-1843 (2015)

Localization of cortical tissue optical changes during seizure activity in vivo with optical coherence tomography
Optical coherence tomography (OCT) is a high resolution, minimally invasive imaging technique, which can...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1812-1827 (2015)

Dual-slit confocal light sheet microscopy for in vivo whole-brain imaging of zebrafish
In vivo functional imaging at single-neuron resolution is an important approach to visualize biological...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1797-1811 (2015)

Ultra-thin and flexible endoscopy probe for optical coherence tomography based on stepwise transitional core fiber
We present an ultra-thin fiber-body endoscopy probe for optical coherence tomography (OCT) which is based on...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1782-1796 (2015)

Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue
Molecular imaging using optical techniques provides insight into disease at the cellular level. In this...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1767-1781 (2015)

Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging
The dosimetry of light-based therapies critically depends on both optical and vascular parameters. We...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1761-1766 (2015)

Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity
Light is a powerful tool to non-invasively probe highly scattering media for clinical applications ranging...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1749-1760 (2015)

Assessment of imaging with extended depth-of-field by means of the light sword lens in terms of visual acuity scale
We present outcomes of an imaging experiment using the refractive light sword lens (LSL) as a contact lens in...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1738-1748 (2015)

Hybrid algorithm for simulating the collimated transmittance of homogeneous stratified turbid media
In this work we describe the development of a program that simulates the propagation of photons through...
Biomedical Optics Express, Vol. 6 Issue 5, pp.1726-1737 (2015)

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Call for Papers

Optical Molecular Probes, Imaging and Drug Delivery
  • Paul French, Irene Georgakoudi, Peter So
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015
Bio-Optics: Design and Application
  • Tomasz Tkaczyk and Chris Xu
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015
Novel Techniques in Microscopy
  • Paul Campagnola and Eric Potma
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015
Optical Trapping Applications
  • Steven Neale and Peter Reece
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015
Optics and the Brain
  • Elizabeth M. C. Hillman, Frederic Leblond, Francesco Pavone, Shy Shoham
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015

Published

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

Spotlight on Optics

Adaptive optics optical coherence tomography at 1 MHz

Almost 25 years after the first demonstration of optical coherence tomography (OCT), it is clear that the image... [more]

Reflection-mode in vivo photoacoustic microscopy with subwavelength lateral resolution

Interest in photoacoustic microscopy has grown tremendously since its first publication in 2005. Photoacoustic imaging... [more]

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Images of Rod Photoreceptors Inside the Living Human Eye

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Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

Biomedical Optics Express - Feature Overview
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Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
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Biomedical Optics Express - Introduction by Joseph Izatt