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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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Polarized light spatial frequency domain imaging for non-destructive quantification of soft tissue fibrous structures
The measurement of soft tissue fiber orientation is fundamental to pathophysiology and biomechanical function...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1520-1533 (2015)

Development of a graded index microlens based fiber optical trap and its characterization using principal component analysis
We demonstrate a miniaturized single beam fiber optical trapping probe based on a high numerical aperture...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1512-1519 (2015)

Broadband miniature optical ultrasound probe for high resolution vascular tissue imaging
An all-optical ultrasound probe for vascular tissue imaging was developed. Ultrasound was generated by pulsed...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1502-1511 (2015)

Measuring the optical characteristics of medulloblastoma with optical coherence tomography
Medulloblastoma is the most common malignant pediatric brain tumor. Standard treatment consists of surgical...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1487-1501 (2015)

Long-term two-photon neuroimaging with a photostable AIE luminogen
In neuroscience, fluorescence labeled two-photon microscopy is a promising tool to visualize ex vivo and in...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1477-1486 (2015)

Differential diagnosis of human bladder mucosa pathologies in vivo with cross-polarization optical coherence tomography
Quantitative image analysis and parameter extraction using a specific implementation of...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1464-1476 (2015)

Temporal and spatial temperature distributions on glabrous skin irradiated by a 1940 nm continuous-wave laser stimulator
For predicting pain stimulation effects and avoiding damage in 1940nm laser evoked potentials (LEPs)...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1451-1463 (2015)

Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography
Quantification of chromophore concentrations in reflectance mode remains a major challenge for biomedical...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1429-1450 (2015)

Real-time tissue differentiation based on optical emission spectroscopy for guided electrosurgical tumor resection
Complete surgical removal of cancer tissue with effective preservation of healthy tissue is one of the most...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1419-1428 (2015)

Imaging of retinal vasculature using adaptive optics SLO/OCT
We use our previously developed adaptive optics (AO) scanning laser ophthalmoscope (SLO)/ optical coherence...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1407-1418 (2015)

Feasibility of terahertz reflectometry for discrimination of human early gastric cancers
We have investigated the feasibility of THz time-domain reflectometry for the discrimination of human early...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1398-1406 (2015)

Dispersion compensation in three-photon fluorescence microscopy at 1,700 nm
Signal generation in three-photon microscopy is proportional to the inverse-squared of the pulse width. Group...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1392-1397 (2015)

Complete 360° circumferential gonioscopic optical coherence tomography imaging of the iridocorneal angle
Clinically, gonioscopy is used to provide en face views of the ocular angle. The angle has been imaged with...
Biomedical Optics Express, Vol. 6 Issue 4, pp.1376-1391 (2015)

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Call for Papers

Optical Molecular Probes, Imaging and Drug Delivery
  • Paul French, Irene Georgakoudi, Peter So
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015
Bio-Optics: Design and Application
  • Tomasz Tkaczyk and Chris Xu
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015
Novel Techniques in Microscopy
  • Paul Campagnola and Eric Potma
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015
Optical Trapping Applications
  • Steven Neale and Peter Reece
  • Submission opens: 1 May 2015; Submission deadline: 15 June 2015

Published

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

Spotlight on Optics

Adaptive optics optical coherence tomography at 1 MHz

Almost 25 years after the first demonstration of optical coherence tomography (OCT), it is clear that the image... [more]

Reflection-mode in vivo photoacoustic microscopy with subwavelength lateral resolution

Interest in photoacoustic microscopy has grown tremendously since its first publication in 2005. Photoacoustic imaging... [more]

What's New

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Video Discussion

Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes

Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes
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Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments

Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments
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Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments

Images of Rod Photoreceptors Inside the Living Human Eye

Images of Rod Photoreceptors Inside the Living Human Eye
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Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

Biomedical Optics Express - Feature Overview
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Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
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Biomedical Optics Express - Introduction by Joseph Izatt