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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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Digitally synthesized beat frequency-multiplexed fluorescence lifetime spectroscopy
Frequency domain fluorescence lifetime imaging is a powerful technique that enables the observation of subtle...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4428-4436 (2014)

Engineering optically triggered droplets for photoacoustic imaging and therapy
Liquid perfluorocarbon (PFC) droplets incorporating optical absorbers can be vaporized through photothermal...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4417-4427 (2014)

Evaluation of flow velocities after carotid artery stenting through split spectrum Doppler optical coherence tomography and computational fluid dynamics modeling
Hemodynamics plays a critical role in the development of atherosclerosis, specifically in regions of curved...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4405-4416 (2014)

Ultrahigh speed endoscopic optical coherence tomography for gastroenterology
We describe an ultrahigh speed endoscopic swept source optical coherence tomography (OCT) system for clinical...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4387-4404 (2014)

Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory
To extend our understanding of tear film dynamics for the management of dry eye disease, we propose a method...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4374-4386 (2014)

Fast monitoring of in-vivo conformational changes in myosin using single scan polarization-SHG microscopy
Fast imaging of molecular changes under high-resolution and label-free conditions are essential for...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4362-4373 (2014)

Miniature objective lens with variable focus for confocal endomicroscopy
Spectrally encoded confocal microscopy (SECM) is a reflectance confocal microscopy technology that can...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4350-4361 (2014)

Monte Carlo modeling of angiographic optical coherence tomography
Optical coherence tomography (OCT) provides both structural and angiographic imaging modes. Because of its...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4338-4349 (2014)

Blood vessel segmentation and width estimation in ultra-wide field scanning laser ophthalmoscopy
Features of the retinal vasculature, such as vessel widths, are considered biomarkers for systemic disease....
Biomedical Optics Express, Vol. 5 Issue 12, pp.4329-4337 (2014)

Quantitative elasticity measurement of urinary bladder wall using laser-induced surface acoustic waves
The maintenance of urinary bladder elasticity is essential to its functions, including the storage and...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4313-4328 (2014)

Accuracy of oxygen saturation and total hemoglobin estimates in the neonatal brain using the semi-infinite slab model for FD-NIRS data analysis
Frequency domain near-infrared spectroscopy (FD-NIRS) is a non-invasive method for measuring optical...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4300-4312 (2014)

In vivo nonlinear spectral imaging as a tool to monitor early spectroscopic and metabolic changes in a murine cutaneous squamous cell carcinoma model
Timely detection of cutaneous squamous cell carcinoma with non-invasive modalities like nonlinear spectral...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4281-4299 (2014)

Wavelet based feature extraction and visualization in hyperspectral tissue characterization
Hyperspectral images of tissue contain extensive and complex information relevant for clinical ...
Biomedical Optics Express, Vol. 5 Issue 12, pp.4260-4280 (2014)

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Published

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published
BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

Spotlight on Optics

Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy

The field of clinical in vivo retinal imaging has recently entered into a new and exciting stage, thanks to the recent... [more]

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

Surgical guidance remains an important, yet underdeveloped, application area of optical imaging techniques. In... [more]

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Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

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Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
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Biomedical Optics Express - Introduction by Joseph Izatt