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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues

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Estimating soft tissue thickness from light-tissue interactions––a simulation study
Immobilization and marker-based motion tracking in radiation therapy often cause decreased patient comfort....
Biomedical Optics Express, Vol. 4 Issue 7, pp.1176-1187 (2013)

Multilayer thin-film phantoms for axial contrast transfer function measurement in optical coherence tomography
In optical coherence tomography (OCT), axial resolution is one of the most critical parameters impacting...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1166-1175 (2013)

3D modeling to characterize lamina cribrosa surface and pore geometries using in vivo images from normal and glaucomatous eyes
En face adaptive optics scanning laser ophthalmoscope (AOSLO) images of the anterior lamina cribrosa surface...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1153-1165 (2013)

Retinal layer segmentation of macular OCT images using boundary classification
Optical coherence tomography (OCT) has proven to be an essential imaging modality for ophthalmology and is...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1133-1152 (2013)

Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology
We developed a micromotor based miniature catheter with an outer diameter of 3.2 mm for ultrahigh speed...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1119-1132 (2013)

Direct identification of breast cancer pathologies using blind separation of label-free localized reflectance measurements
Breast tumors are blindly identified using Principal (PCA) and Independent Component Analysis (ICA) of...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1104-1118 (2013)

Multiple contrast metrics from the measurements of a digital confocal microscope
We describe various methods to process the data collected with a digital confocal microscope (DCM) in order...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1091-1103 (2013)

In vitro measurements of physiological glucose concentrations in biological fluids using mid-infrared light
Mid-infrared transmission spectroscopy using broadband mid-infrared or Quantum Cascade laser sources is used...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1083-1090 (2013)

Integrated fluorescence correlation spectroscopy device for point-of-care clinical applications
We describe an optical system which reduces the cost and complexity of fluorescence correlation spectroscopy...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1074-1082 (2013)

Three-dimensional mapping of oxygen tension in cortical arterioles before and after occlusion
Occlusions in single cortical microvessels lead to a reduction in oxygen supply, but this decrement has not...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1061-1073 (2013)

A method for detecting forward scattering signals on-chip with a photonic-microfluidic integrated device
A photonic integrated microfluidic device is demonstrated to perform optical excitation and forward scatter...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1051-1060 (2013)

Fiber-optic OCT sensor guided “SMART” micro-forceps for microsurgery
A handheld Smart Micromanipulation Aided Robotic-surgery Tool (SMART) micro-forceps guided by a fiber-optic...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1045-1050 (2013)

Versatile optical coherence tomography for imaging the human eye
We demonstrated the feasibility of a CMOS-based spectral domain OCT (SD-OCT) for versatile ophthalmic...
Biomedical Optics Express, Vol. 4 Issue 7, pp.1031-1044 (2013)

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Call for Papers

Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice and James Tunnell
  • Submission Deadline: 31 July 2013
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Submission Deadline: 15 June 2013
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Submission Deadline: 15 June 2013
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Submission Deadline: 15 June 2013
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Submission Deadline: 15 June 2013

Published

BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published
Cellular Imaging of the Retina
  • Joseph Carroll, Michael Pircher, Robert J. Zawadzki
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

Video Discussion

Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes

Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes
Views: 167
Bilal Khan, Univ. Texas Arlington, discusses a brush optode to improve optical contact with the scalp for brain function imaging.

Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments

Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments
Views: 274
Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments

Images of Rod Photoreceptors Inside the Living Human Eye

Images of Rod Photoreceptors Inside the Living Human Eye
Views: 2179
Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

Biomedical Optics Express - Feature Overview
Views: 378
Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
Views: 579
Biomedical Optics Express - Introduction by Joseph Izatt

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Spotlight on Optics

Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT

In the latest paper from Robert Huber’s group, Thomas Klein presents the joined aperture OCT (JA-OCT) detection scheme,... [more]

A GAMOS plug-in for GEANT4 based Monte Carlo simulation of radiation-induced light transport in biological media

Cerenkov light emission from beta-emitting radionuclides was first measured in biological tissue less than five years... [more]

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