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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2012 Impact Factor: 3.176

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In vivo mouse fluorescence imaging for folate-targeted delivery and release kinetics
Many cancer cells over-express folate receptors, and this provides an opportunity for both folate-targeted...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2662-2678 (2014)

Bone tissue phantoms for optical flowmeters at large interoptode spacing generated by 3D-stereolithography
A bone tissue phantom prototype allowing to test, in general, optical flowmeters at large interoptode...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2715-2725 (2014)

Optical design and evaluation of a 4 mm cost-effective ultra-high-definition arthroscope
High definition and magnification rigid endoscope plays an important role in modern minimally invasive...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2697-2714 (2014)

Surface modification of silica particles with gold nanoparticles as an augmentation of gold nanoparticle mediated laser perforation
Gold nanoparticle mediated (GNOME) laser transfection/perforation fulfills the demands of a reliable...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2686-2696 (2014)

In vivo quantitative photoacoustic microscopy of gold nanostar kinetics in mouse organs
We developed a high-resolution photoacoustic microscopy (PAM) system with a near-infrared (NIR) laser to...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2679-2685 (2014)

Calcium imaging at kHz frame rates resolves millisecond timing in neuronal circuits and varicosities
We have configured a widefield fast imaging system that allows imaging at 1000 frames per second (512x512...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2648-2661 (2014)

High resolution three-dimensional photoacoutic tomography with CCD-camera based ultrasound detection
A photoacoustic tomograph based on optical ultrasound detection is demonstrated, which is capable of high...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2635-2647 (2014)

In vivo imaging of functional microvasculature within tissue beds of oral and nasal cavities by swept-source optical coherence tomography with a forward/side-viewing probe
We report three-dimensional (3D) imaging of microcirculation within human cavity tissues in vivo using a...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2620-2634 (2014)

Direct observation and validation of fluorescein tear film break-up patterns by using a dual thermal-fluorescent imaging system
The fluorescein tear film break-up test is a common tear film stability test for dry eye diagnosis. This test...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2614-2619 (2014)

Quantitative 3D-OCT motion correction with tilt and illumination correction, robust similarity measure and regularization
Variability in illumination, signal quality, tilt and the amount of motion pose challenges for...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2591-2613 (2014)

Optimized approaches for optical sectioning and resolution enhancement in 2D structured illumination microscopy
The use of structured illumination in fluorescence microscopy allows the suppression of out of focus light...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2580-2590 (2014)

Improving high resolution retinal image quality using speckle illumination HiLo imaging
Retinal image quality from flood illumination adaptive optics (AO) ophthalmoscopes is adversely affected by...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2563-2579 (2014)

Characterization and in-vivo evaluation of a multi-resolution foveated laparoscope for minimally invasive surgery
The state-of-the-art laparoscope lacks the ability to capture high-magnification and wide-angle images...
Biomedical Optics Express, Vol. 5 Issue 8, pp.2548-2562 (2014)

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In Progress

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • In Progress (no new submissions accepted)

Published

Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published
BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

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Spotlight on Optics

Optical multichannel room temperature magnetic field imaging system for clinical application

Magnetic field imaging (MFI) is a contact free cardiac imaging method, which detects the electromagnetic signals of the... [more]

In vitro characterization of genetically expressed absorbing proteins using photoacoustic spectroscopy

Photoacoustic imaging has been developed as a hybrid biomedical imaging modality where light is utilized to activate... [more]

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Biomedical Optics Express - Introduction by Joseph Izatt