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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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A wide field-of-view scanning endoscope for whole anal canal imaging
We report a novel wide field-of-view (FOV) scanning endoscope, the AnCam, which is based on contact image...
Biomedical Optics Express, Vol. 6 Issue 2, pp.607-614 (2015)

Quantitative polarized light microscopy of human cochlear sections
Dysfunction of the inner ear is the most common cause of sensorineural hearing loss, which is the most common...
Biomedical Optics Express, Vol. 6 Issue 2, pp.599-606 (2015)

Phthalocyanine photosensitizers as contrast agents for in vivo photoacoustic tumor imaging
There is a need for contrast agents for non-invasive diagnostic imaging of tumors. Herein, Multispectral...
Biomedical Optics Express, Vol. 6 Issue 2, pp.591-598 (2015)

In vivo imaging of human photoreceptor mosaic with wavefront sensorless adaptive optics optical coherence tomography
Wavefront sensorless adaptive optics optical coherence tomography (WSAO-OCT) is a novel imaging technique for...
Biomedical Optics Express, Vol. 6 Issue 2, pp.580-590 (2015)

Microscopy illumination engineering using a low-cost liquid crystal display
Illumination engineering is critical for obtaining high-resolution, high-quality images in microscope...
Biomedical Optics Express, Vol. 6 Issue 2, pp.574-579 (2015)

Optical metabolic imaging quantifies heterogeneous cell populations
The genetic and phenotypic heterogeneity of cancers can contribute to tumor aggressiveness, invasion, and...
Biomedical Optics Express, Vol. 6 Issue 2, pp.559-573 (2015)

Digital separation of diaminobenzidine-stained tissues via an automatic color-filtering for immunohistochemical quantification
The digital separation of diaminobenzidine (DAB)-stained tissues from hematoxylin background is an important...
Biomedical Optics Express, Vol. 6 Issue 2, pp.544-558 (2015)

Noninvasive photoacoustic measurement of the composite indicator dilution curve for cardiac output estimation
Recently, the measurement of indicator dilution curves using a photoacoustic (PA) technology was reported,...
Biomedical Optics Express, Vol. 6 Issue 2, pp.536-543 (2015)

In vivo wide-field reflectance/fluorescence imaging and polarization-sensitive optical coherence tomography of human oral cavity with a forward-viewing probe
We report multimodal imaging of human oral cavity in vivo based on simultaneous wide-field...
Biomedical Optics Express, Vol. 6 Issue 2, pp.524-535 (2015)

Three-wavelength light control of freely moving Drosophila Melanogaster for less perturbation and efficient social-behavioral studies
We developed a real-time automated laser-tracking system combined with continuous wave 1064-nm infrared or...
Biomedical Optics Express, Vol. 6 Issue 2, pp.514-523 (2015)

Measurements of the thermal coefficient of optical attenuation at different depth regions of in vivo human skins using optical coherence tomography: a pilot study
We present detailed measurement results of optical attenuation’s thermal coefficients (referenced to...
Biomedical Optics Express, Vol. 6 Issue 2, pp.500-513 (2015)

High-throughput multiphoton-induced three-dimensional ablation and imaging for biotissues
In this study, a temporal focusing-based high-throughput multiphoton-induced ablation system with...
Biomedical Optics Express, Vol. 6 Issue 2, pp.491-499 (2015)

Fabrication of three-dimensional multi-protein microstructures for cell migration and adhesion enhancement
In this study, three-dimensional (3D) multi-component microstructures were precisely fabricated via...
Biomedical Optics Express, Vol. 6 Issue 2, pp.480-490 (2015)

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Published

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published
BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

Spotlight on Optics

Reflection-mode in vivo photoacoustic microscopy with subwavelength lateral resolution

Interest in photoacoustic microscopy has grown tremendously since its first publication in 2005. Photoacoustic imaging... [more]

Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy

The field of clinical in vivo retinal imaging has recently entered into a new and exciting stage, thanks to the recent... [more]

What's New

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Video Discussion

Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes

Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes
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Bilal Khan, Univ. Texas Arlington, discusses a brush optode to improve optical contact with the scalp for brain function imaging.

Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments

Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments
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Quantitative OCT-based corneal topography in keratoconus with intracorneal ring segments

Images of Rod Photoreceptors Inside the Living Human Eye

Images of Rod Photoreceptors Inside the Living Human Eye
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Alfredo Dubra, University of Rochester, reports new imaging techniques critical for early detection of eye disease.

Biomedical Optics Express - Feature Overview

Biomedical Optics Express - Feature Overview
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Greg Faris, Deputy Editor-in-Chief for Biomedical Optics Express, reviews the features of the new journal.

Introduction to Biomedical Optics Express

Introduction to Biomedical Optics Express
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Biomedical Optics Express - Introduction by Joseph Izatt