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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe
Scanning laser ophthalmoscopes (SLOs) are able to achieve superior contrast and axial sectioning capability...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3204-3216 (2014)

Scalable multiplexing for parallel imaging with interleaved optical coherence tomography
We demonstrate highly parallel imaging with interleaved optical coherence tomography (iOCT) using an...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3192-3203 (2014)

Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy
Eye motion is a major impediment to the efficient acquisition of high resolution retinal images with the...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3174-3191 (2014)

Fully automated side branch detection in intravascular optical coherence tomography pullback runs
Side branches in the atherosclerotic lesion region are important as they highly influence the treatment...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3160-3173 (2014)

Dual modality optical coherence and whole-body photoacoustic tomography imaging of chick embryos in multiple development stages
Chick embryos are an important animal model for biomedical studies. The visualization of chick embryos,...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3150-3159 (2014)

Preparation of a skin equivalent phantom with interior micron-scale vessel structures for optical imaging experiments
A popular alternative of preparing multilayer or microfluidic chip based phantoms could have helped to...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3140-3149 (2014)

Ambiguity of mapping the relative phase of blood pulsations
Blood pulsation imaging (BPI) is a non-invasive optical method based on photoplethysmography (PPG). It is...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3123-3139 (2014)

Multimodal nonlinear optical microscopic imaging provides new insights into acetowhitening mechanisms in live mammalian cells without labeling
We developed a multimodal nonlinear optical microscopy imaging (e.g., third-harmonic generation (THG) and...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3116-3122 (2014)

Sensitivity of MRI-guided near-infrared spectroscopy clinical breast exam data and its impact on diagnostic performance
In this study, data from breast MRI-guided near infrared spectroscopy (NIRS) exams delivered to 44 patients...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3103-3115 (2014)

Three-dimensional optical coherence micro-elastography of skeletal muscle tissue
In many muscle pathologies, impairment of skeletal muscle function is closely linked to changes in the...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3090-3102 (2014)

Time-resolved fluorescence lifetime for cutaneous melanoma detection
Melanoma is the most aggressive skin cancer type. It is characterized by pigmented lesions with high tissue...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3080-3089 (2014)

Design of miniaturized illumination for transvaginal co-registered photoacoustic and ultrasound imaging
A novel lens-array based illumination design for a compact co-registered photoacoustic/ultrasound...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3074-3079 (2014)

Non-common path aberration correction in an adaptive optics scanning ophthalmoscope
The correction of non-common path aberrations (NCPAs) between the imaging and wavefront sensing channel in a...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3059-3073 (2014)

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In Progress

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • In Progress (no new submissions accepted)

Published

Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published
BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

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Spotlight on Optics

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

Surgical guidance remains an important, yet underdeveloped, application area of optical imaging techniques. In... [more]

Noninvasive in-vehicle alcohol detection with wavelength-modulated differential photothermal radiometry

The development of techniques that can non-invasively and reliably detect whether an individual is alcohol-impaired... [more]

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Biomedical Optics Express - Introduction by Joseph Izatt