About the Journal

Biomedical Optics Express will become OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues

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Remote switching of cellular activity and cell signaling using light in conjunction with quantum dots
Stimulating cells by using light is a non-invasive technique that provides flexibility in probing different...
Biomedical Optics Express, Vol. 3 Issue 3, pp.447-454 (2012)

Mechanisms of nanoparticle-mediated photomechanical cell damage
Laser-assisted killing of gold nanoparticle targeted macrophages was investigated. Using pressure transient...
Biomedical Optics Express, Vol. 3 Issue 3, pp.435-446 (2012)

Determining the optical properties of a gelatin‑TiO₂ phantom at 780 nm
Tissue phantoms play a central role in validating biomedical imaging techniques. Here we employ a series of...
Biomedical Optics Express, Vol. 3 Issue 3, pp.418-434 (2012)

Compensation method for obtaining accurate, sub-micrometer displacement measurements of immersed specimens using electronic speckle interferometry
We proposed and validated a compensation method that accounts for the optical distortion inherent in...
Biomedical Optics Express, Vol. 3 Issue 3, pp.407-417 (2012)

Multicolour single molecule imaging on cells using a supercontinuum source
Multicolour single molecule fluorescence imaging enables the study of multiple proteins in the membranes of...
Biomedical Optics Express, Vol. 3 Issue 3, pp.400-406 (2012)

Endovascular optical coherence tomography intensity kurtosis: visualization of vasa vasorum in porcine carotid artery
Application of speckle variance optical coherence tomography (OCT) to endovascular imaging faces difficulty...
Biomedical Optics Express, Vol. 3 Issue 3, pp.388-399 (2012)

Experimental validation of an extended Jones matrix calculus model to study the 3D structural orientation of the collagen fibers in articular cartilage using polarization-sensitive optical coherence tomography
We report results to verify a theoretical framework to analyze the 3D depth-wise structural organization of...
Biomedical Optics Express, Vol. 3 Issue 3, pp.378-387 (2012)

Parametric imaging of the local attenuation coefficient in human axillary lymph nodes assessed using optical coherence tomography
We report the use of optical coherence tomography (OCT) to determine spatially localized optical attenuation...
Biomedical Optics Express, Vol. 3 Issue 2, pp.366-379 (2012)

Label-free imaging of zebrafish larvae in vivo by photoacoustic microscopy
Zebrafish play an important role in biological and biomedical research. Traditional in vivo imaging methods...
Biomedical Optics Express, Vol. 3 Issue 2, pp.360-365 (2012)

Scanning and non-scanning surface plasmon microscopy to observe cell adhesion sites
We observe adhesion sites of a cell on a substrate with high resolution. Since this observation requires...
Biomedical Optics Express, Vol. 3 Issue 2, pp.354-359 (2012)

Detection of single fluorescent proteins inside eukaryotic cells using two-photon fluorescence
Imaging single fluorescent proteins in a live cell is a challenging task because of the strong cellular...
Biomedical Optics Express, Vol. 3 Issue 2, pp.340-353 (2012)

Exploratory Dijkstra forest based automatic vessel segmentation: applications in video indirect ophthalmoscopy (VIO)
We present a methodology for extracting the vascular network in the human retina using Dijkstra’s...
Biomedical Optics Express, Vol. 3 Issue 2, pp.327-339 (2012)

Enhanced robustness digital holographic microscopy for demanding environment of space biology
We describe an optimized digital holographic microscopy system (DHM) suitable for high-resolution...
Biomedical Optics Express, Vol. 3 Issue 2, pp.313-326 (2012)

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Topics in Current Issue

Vol. 3, Iss. 2 — Feb. 1, 2012  pp: 215–379

	Active and Adaptive Optics (1)
	Cell Studies (3)
	Functional Imaging (1)
	Image Processing (2)
	Microfluidics (1)
	Microscopy (1)
	Ophthalmology Applications (1)
	Optical Coherence Tomography (2)
	Optics in Cancer Research (1)
	Photoacoustic Imaging and Spectroscopy (1)

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In Progress

Published

In vivo Microcirculation Imaging
	Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang Published

Cellular Imaging of the Retina
	Joseph Carroll, Michael Pircher, Robert J. Zawadzki Published

Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy
	Xingde Li, Paul Beard, and Irene Georgakoudi Published

Optical Imaging and Spectroscopy
	Andreas Hielscher, Mary-Ann Mycek, and Lev T. Perelman Published

Bio-Optics in Clinical Application, Nanotechnology, and Drug Discovery
	Robert J. Nordstrom, Adah Almutairi, and Elizabeth Hillman Published

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