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Biomedical Optics Express

Biomedical Optics Express

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About the Journal

Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.

Editor-in-Chief: Joseph A. Izatt, Duke University
eISSN: 2156-7085
Frequency: Rapid article-at-a-time publication, Monthly issues
2013 Impact Factor: 3.497

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Correlative multicolor 3D SIM and STORM microscopy
Within the last decade, super-resolution methods that surpass the diffraction limit of light microscopy have...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3326-3336 (2014)

Wide field intravital imaging by two-photon-excitation digital-scanned light-sheet microscopy (2p-DSLM) with a high-pulse energy laser
Digital-scanned light-sheet microscopy (DSLM) illuminates a sample in a plane and captures...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3311-3325 (2014)

FPscope: a field-portable high-resolution microscope using a cellphone lens
The large consumer market has made cellphone lens modules available at low-cost and in high-quality. In a...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3305-3310 (2014)

Wavelet transform fast inverse light scattering analysis for size determination of spherical scatterers
We present a fast approach for size determination of spherical scatterers using the continuous wavelet...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3292-3304 (2014)

Pixel-based absorption correction for dual-tracer fluorescence imaging of receptor binding potential
Ratiometric approaches to quantifying molecular concentrations have been used for decades in microscopy, but...
Biomedical Optics Express, Vol. 5 Issue 10, pp.3280-3291 (2014)

Quantitative analysis of intrinsic skin aging in dermal papillae by in vivo harmonic generation microscopy
Chronological skin aging is associated with flattening of the dermal-epidermal junction (DEJ), but to date no...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3266-3279 (2014)

Raman difference spectroscopy: a non-invasive method for identification of oral squamous cell carcinoma
The feasibility of shifted-excitation Raman difference spectroscopy (SERDS) as a label-free and non-invasive...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3252-3265 (2014)

Evaluation of antibiotic effects on Pseudomonas aeruginosa biofilm using Raman spectroscopy and multivariate analysis
We investigate the mode of action and classification of antibiotic agents (ceftazidime, patulin, and...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3238-3251 (2014)

Remote diffuse reflectance spectroscopy sensor for tissue engineering monitoring based on blind signal separation
In this study the first results on evaluation and assessment of grafted bioengineered skin substitutes using...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3231-3237 (2014)

Optical coherence Doppler tomography for quantitative cerebral blood flow imaging
Optical coherence Doppler tomography (ODT) is a promising neurotechnique that permits 3D imaging of the...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3217-3230 (2014)

True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe
Scanning laser ophthalmoscopes (SLOs) are able to achieve superior contrast and axial sectioning capability...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3204-3216 (2014)

Scalable multiplexing for parallel imaging with interleaved optical coherence tomography
We demonstrate highly parallel imaging with interleaved optical coherence tomography (iOCT) using an...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3192-3203 (2014)

Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy
Eye motion is a major impediment to the efficient acquisition of high resolution retinal images with the...
Biomedical Optics Express, Vol. 5 Issue 9, pp.3174-3191 (2014)

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In Progress

Topics in Biomedical Optics from OSA's BIOMED 2014 Conference
  • Stefan Andersson-Engels, Stephen Boppart, Vadim Backman, Christoph Hitzenberger (Lead)
  • In Progress (no new submissions accepted)

Published

Advances in Optics for Biotechnology, Medicine and Surgery
  • Maryann Fitzmaurice, Brian Pogue, Guillermo Tearney, James Tunnell, and Changhuei Yang
  • Published
Bio-Optics: Design and Application
  • Guoqiang Li and Rongguang Liang
  • Published
Optical Trapping Applications
  • Carlos Lopez-Mariscal and David McGloin
  • Published
Novel Techniques in Microscopy
  • Jerome Mertz and Eric Potma
  • Published
Optical Molecular Probes, Imaging, and Drug Delivery
  • Paul Campagnola, Paul French, Irene Georgakoudi, and Mary-Ann Mycek
  • Published
BIOMED 2012
  • Vadim Backman, Stanislav Emelianov, Christoph Hitzenberger, Brian Pogue, Peter So, and Valery Tuchin
  • Published
Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices
  • Robert J. Nordstrom, Jeeseong Hwang, and Jessica Ramella-Roman
  • Published
Advances in Optics for Biotechnology, Medicine and Surgery
  • Irving Bigio, Daniel Elson, Elizabeth Hillman, Richard Levenson, and Peter So
  • Published
In vivo Microcirculation Imaging
  • Andrew Dunn, Rainer Leitgeb, Ruikang K. Wang, Hao F. Zhang
  • Published

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Interactive Science Publishing

Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).

OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.

Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.

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Spotlight on Optics

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

Surgical guidance remains an important, yet underdeveloped, application area of optical imaging techniques. In... [more]

Noninvasive in-vehicle alcohol detection with wavelength-modulated differential photothermal radiometry

The development of techniques that can non-invasively and reliably detect whether an individual is alcohol-impaired... [more]

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Biomedical Optics Express - Introduction by Joseph Izatt