About the Journal
Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life sciences. The journal scope encompasses theoretical modeling and simulations, technology development, and biomedical studies and clinical applications.
Editor-in-Chief: Joseph A. Izatt, Duke University
Frequency: Rapid article-at-a-time publication, Monthly issues
2012 Impact Factor: 3.176
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Motion-artifact-robust, polarization-resolved second-harmonic-generation microscopy based on rapid polarization switching with electro-optic Pockells cell and its application to in vivo visualization of collagen fiber orientation in human facial skin
Polarization-resolved second-harmonic-generation (PR-SHG) microscopy is a powerful tool for investigating...
Biomedical Optics Express, Vol. 5 Issue 4, pp.1099-1113 (2014)
Spectral OCT with speckle contrast reduction for evaluation of the healing process after PRK and transepithelial PRK
We evaluate Spectral OCT (SOCT) with a speckle contrast reduction technique using resonant scanner for...
Biomedical Optics Express, Vol. 5 Issue 4, pp.1089-1098 (2014)
Contact-free monitoring of circulation and perfusion dynamics based on the analysis of thermal imagery
Acute circulatory disorders are commonly associated with systemic inflammatory response (SIRS) and sepsis....
Biomedical Optics Express, Vol. 5 Issue 4, pp.1075-1089 (2014)
Multiple-object geometric deformable model for segmentation of macular OCT
Optical coherence tomography (OCT) is the de facto standard imaging modality for ophthalmological assessment...
Biomedical Optics Express, Vol. 5 Issue 4, pp.1062-1074 (2014)
Photonic integrated Mach-Zehnder interferometer with an on-chip reference arm for optical coherence tomography
Optical coherence tomography (OCT) is a noninvasive, three-dimensional imaging modality with several medical...
Biomedical Optics Express, Vol. 5 Issue 4, pp.1050-1061 (2014)
Effect of temperature and fixation on the optical properties of atherosclerotic tissue: a validation study of an ex-vivo whole heart cadaveric model
Atherosclerotic plaque composition can be imaged using the optical attenuation coefficient derived from...
Biomedical Optics Express, Vol. 5 Issue 4, pp.1038-1049 (2014)
Accurate position tracking of optically trapped live cells
Optical trapping is a powerful tool in Life Science research and is becoming common place in many microscopy...
Biomedical Optics Express, Vol. 5 Issue 4, pp.1026-1037 (2014)
Nanosecond laser pulse stimulation of spiral ganglion neurons and model cells
Optical stimulation of the inner ear has recently attracted attention, suggesting a higher frequency...
Biomedical Optics Express, Vol. 5 Issue 4, pp.1014-1025 (2014)
Optical stimulation enables paced electrophysiological studies in embryonic hearts
Cardiac electrophysiology plays a critical role in the development and function of the heart. Studies of...
Biomedical Optics Express, Vol. 5 Issue 4, pp.1000-1013 (2014)
Continuous noninvasive monitoring of changes in human skin optical properties during oral intake of different sugars with optical coherence tomography
The objective of this study was to evaluate the effects of blood glucose concentration (BGC) on in vivo human...
Biomedical Optics Express, Vol. 5 Issue 4, pp.990-999 (2014)
Reliable recovery of the optical properties of multi-layer turbid media by iteratively using a layered diffusion model at multiple source-detector separations
Accurately determining the optical properties of multi-layer turbid media using a layered diffusion model is...
Biomedical Optics Express, Vol. 5 Issue 3, pp.975-989 (2014)
In vivo adaptive optics microvascular imaging in diabetic patients without clinically severe diabetic retinopathy
We used a confocal adaptive optics scanning laser ophthalmoscope (AOSLO) to image the retina of subjects with...
Biomedical Optics Express, Vol. 5 Issue 3, pp.961-974 (2014)
Spatial light modulator based active wide-field illumination for ex vivo and in vivo quantitative NIR FRET imaging
Fluorescence lifetime imaging is playing an increasing role in drug development by providing a sensitive...
Biomedical Optics Express, Vol. 5 Issue 3, pp.944-960 (2014)
Topics in Current Issue
Vol. 5, Iss. 3 — Mar. 1, 2014 pp: 653–989
Call for Papers
|Topics in Biomedical Optics from OSA's BIOMED 2014 Conference|
|Advances in Optics for Biotechnology, Medicine and Surgery|
|Bio-Optics: Design and Application|
|Optical Trapping Applications|
|Novel Techniques in Microscopy|
|Optical Molecular Probes, Imaging, and Drug Delivery|
|Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices|
|Advances in Optics for Biotechnology, Medicine and Surgery|
|In vivo Microcirculation Imaging|
Authors are encouraged to submit manuscripts that use the special features of Biomedical Optics Express that are particularly germane to the biomedical content, such as inclusion of external high-resolution image files, movies, and interactive science publishing (ISP).
OSA ISP is an image viewing application developed by OSA in cooperation with Kitware, Inc., and the National Library of Medicine. The software allows interactive viewing of a wide range of 2D and 3D image data formats including DICOM, TIFF, and JPEG images. Authors can use the tool to build custom views of image data that can be saved, integrated with peer-reviewed articles, and shared with readers through the OSA journals.
Questions about the OSA ISP software can be directed to ISPHelp@osa.org or (202) 416-1938.
Photoacoustic imaging has been developed as a hybrid biomedical imaging modality where light is utilized to activate... [more]
Transgenic and knockout mouse models have increased our understanding of the structure and function of the normal eye... [more]
- Feb 24 2014 : Thicker than Water: Medical Researchers Use Light to Quickly and Easily Measure Blood’s Clotting Properties - To provide caregivers with timely information about the clotting... more
- Feb 18 2014 : A Stretchable Highway for Light - A team of Belgian researchers reports progress on this front with... more
- Feb 11 2014 : First 3-D Movies of Living Sperm - more