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Optica Publishing Group
  • Chinese Optics Letters
  • Vol. 3,
  • Issue S1,
  • pp. S26-S27
  • (2005)

Deformation and cleavage of microtubules studied with optical tweezers

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Abstract

The mechanical properties of fluorescent microtubules (MTs) are probed with dual-optical tweezers system. The results indicate that the fluorescent MTs are much easier to be extended compared with those without fluorescence. Such MT can be extended by 30% and force for breaking up it is only several piconewtons. Furthermore, we find that the breakup of the protofilaments is not simultaneous but step-by-step. Finally, the mechanism of the breaking is discussed.

© 2005 Chinese Optics Letters

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